I also have a five year old son with CF. Sean hasn't had nearly as many admissions as your son, but he also has expressed a lot of anger and frustration about CF recently. A few months ago he actually asked his daddy, "Why did God make me with CF." And I don't think a week goes by that he doesn't tell us that he "doesn't like CF." So far he does well with his enzymes, medicines, etc., but he will frequently fight us about his "vest" treatment. I think part of it is his age. Before this year, he basically accepted his treatments as a "normal" part of his day. However, five is a big year. They are no longer babies. Sean, himself, is an active, inquisitive little boy. I think he is able to think more for himself - he knows that his friends and sisters don't have CF and I think he thinks he feels angry and different. I actually posted on this board a month ago ("CF Pen Pal") asking if anyone is interested in having Sean "write" to them and have them write back. He now has two pen pals and I think it has helped alot. If you think it might help your son, I am sure Sean would like another "pal" - someone that he can talk to about CF, as well as normal five year old things.When it is time for Sean's treatments, we try to give him some power by giving him choices. We let him choose what activity he wants to do during his treatments. For his birthday last month, we actually bought him a Play Station 2 that is ONLY to be used during treatments. He loves that game and it helps him have something to which look forward. If that doesn't work, I then give him two more choices. I tell him that he can either do his treatments and not like them and be sad and grumpy or that he can do his treatments and find a way to like them and be happy. I tell him that it is his choice, but I certainly hope he chooses to be happy. I know that sounds a little extreeme, but I don't want his treatments to ever be an option. In everyone's life and especially his, there are always things that we don't want to do, but have to do. I do emphasize with him and let him know that I know it isn't easy doing treatments, and I tell him that is why we give him choices. Sean also occasionally has thrown big fits about his treatments. I treat it the same way that I do with any other fit. I either put him in a time-out or take away a privilege (ie. one of his toys, etc.). And then, on other days when he is doing his treatments nicely, I try to sit down with him and spend some time with him, or at least praise him and tell him he is doing a good job.Sean also has been getting angry about non-CF things (cleaning his room, etc.). I have been trying to figure out if it is repressed anger because of his CF or if it is just a "stage." I do know from talking to friends of children who don't have CF, that all their five-year-olds also are having "power" and "anger" issues, as well. With CF, Sean just has one more thing to be angry about. The only reason I mention this is because I think mostly it is an age thing. Our sons are becoming their own people and with that they are going to have their own thoughts and ideas. With that, they are going to question things. In your son's mind, it makes sense to him that maybe if he stops all this medicine business, maybe it will just all go away. I think you are doing the right thing. I would continue to talk him through his treatments and enforce to him that this is something he has to do. Try to give him reasonable choices so that he feels that he has some power. I wish you and your son lots of luck. I hope I have helped a little.Katrina - mother of Sean (5) w/cf, Carolyn (almost 4) w/o cf, and Allison (almost 2) w/o cfrobertnkatrina@comcast.net