Hi, I just healed a chronic sinus infection that I had for about 7 years, by drinking water. I am an adult, and I drank a gallon to a gallon-and-a-half a day, but I think that's more than most adults would need. (I live in a dry frozen climate -- minnesota winter -- and I have trouble staying hydrated. It also worked better for my sinuses when I added salt to some of the water -- 1/4 tsp per quart. (I added the salt to about half of the water I drank --- if I added salt to all the water I got constipated, too much salt per water intake for me. People are all different.) I got this recipe from the "watercure" website -- sorry don't know exact name but if you search on that, all one word, you'd find it. I don't know if your niece would need the salt if she gets enough salt in her diet -- I cook all my own food and was salt-deficient, so I could be different. But definitely, would help if she drinks a lot of water. Thick mucous that doesn't drain right is a classic sign of dehydration -- I know it is for CF too, but it wouldn't be good to have both dehydration and CF. And look into her salt intake -- if a person doesn't have enough salt, she can't absorb water effectively and the water will run right through her. Salt is how your body absorbs water, water is drawn into digestive tract cells by the salt. You might also do a search on salt deficiency and mucous, because I remember reading that a sign of salt deficiency is thick mucous in the lungs, which wouldn't be good on top of CF. (I've got gunk in my lungs from lack of salt and I don't have CF.) I also follow a diet, Peter D'Adamo's Eat Right 4 Your Type diet (think website is dadamo.com) -- it has been very effective over time, in strengthening my immune system. It's a "get healthy" diet, not a lose-weight diet, though some people lose weight on it. You also might want to research fatty acids, things called omega 3 & omega 6 fatty acids found in oils. Udo Erasmus' book "Fats that heal, fats that kill" is a great explanation -- or see his detailed website udoerasmus.com (I think?). Fatty acids are things most people aren't eating right, and they have an enormous impact on levels of inflammation and immune system function. Many people are deficient in omega 3 fatty acids especially, and I read that omega 3 fatty acids are antimicrobial against staph (can't vouch for whether that source was reliable, but it makes sense from what I know about fatty acids.) Anyway, someone deficient in fatty acids would surely have lower immunity to staph. Omega 3's are found in flax oil, so for an adult 1-2 tablespoons a day would help -- I put it in fruit smoothies. But read the Erasmus book -- it's important to know more. The balance of fatty acids in the oils is important, and a different oil like hemp might work better for some people depending on how they eat. It's not as complicated as it sounds. A great comprehensive book on nutrients is Garrison & Somer's "Nutrition Desk Reference" -- I make sure I get all the vitamins & minerals in there, and it's made a huge impact on my health. Lastly, I've heard that about oregano oil & staph too. I'm fighting a staph infection right now. Also check out olive leaf extract -- I'm reading it has strong antimicrobial properties, and might really help with the staph. It is helping me. Good luck with your niece! I was just stopping by, so if you answer I probably won't see it, but I wish you well. (o: