My daughters have been on Prilosec and Zantac over the years. My oldest one is now on Prevacid, and it seems to being helping her. My youngest is on generic Prilosec, and handles that good too. My younger one suffered terrible reflux, so we tried everything with her as an infant.
We have over the years tried taking them off these, but they do not gain weight without them. These medications really have helped in making the enzymes work better.
My oldest one was having horrible stomach aches every morning, and we started giving her 1 dose of Prevacid in the morning and 1 in the evening, and the stomach aches went away and the weight gain started going full force. Sometimes I am amazed at what a difference can be seen by just changing something as simple as adding a dose in the evening!