Actually we have reduced some medications. DS' doctor retired about a year ago and we are now with a new CF clinic. DS was probably on more medications than the average person wcf because his primary doctor was an infectious disease specialist and VERY VERY proactive. I didn't really attribute it to his being on Orkambi, now symdeko, but based on blood test results they stopped Vitamin K, Actigal and supplemental Vitamin A. He still takes a CF multi-vitamin and additional Vitamin K. Recent appointment the removed a prophylactic antibiotic he'd been on since a toddler, which his previous doctor had him on. He still takes Azithromycin and Bactrim (due to steno maltophilia cultures that pop up from time to time). Another change was removing his atrovent neb. He still nebs albuterol, but they added Hypersal. They did mention reducing vest treatments from the 3 a day he does to two, but I'm not quite comfortable with that and unless there's a scheduling conflict after school, we don't have an issue with keeping that treatment as he's home anyway, playing video games with friends in his room.