antibiotic reactions

[anonymous]

I was just wondering if anyone else is allgeric to the following meds Ciprofloxacin, ceftazidime ceftriaxone and meropenem. My daughter last March 03 (she is 11 now) had been in and out on iv's since Nov of the following year due to poor PFT results. She had a reaction after 4 days of Timentin and tobramycin iv's so they stopped the Timentin (thinkin that was the cause) she still had reactions, so they stopped the tobra. They decided to do some allergy tests and the rest is history. They continued back on the tim/tob and with the help of some anithestamine we got thru the " tune up". We just went back in again after 18mths with no infections, and she again reacted after the Tobra was introduced. However they did another allergy test on the Tobra and it came up clear, however she still reacted but only very mildly. Is there anyone out there that has know allgeries to any of the above as they say its rare to have them to Tobra. It is also going to make treating her as she gets older as we are limited to the drugs we can use. We live in Australia so our drugs might have different names. She also reacted to Roxithromycin too so thats another one of the list. Also she does not produce much sputum etc and never has, was looking into those vests but out here they dont seem to go for them. What do you guys think of them?
rgds paula

 

[Jo]

hi there, i live in ireland so i havent heard of most of those.. we dont use the vest over here, i use a p.e.p mask and it works pretty well for me.

 

[anonymous]

I never produced much sputum until I got to college, so she may just not have a lot right now. Is she on Pulmozyme? It's the only drug SPECIFFICAL, for treating CF. It's also called DNAse. It is inhaled in a nebulizer and physically breaks up the DNA of mucus so it is thinner and eaiser to expell.
What kind of reaction was she having to her meds. I am sensitive to cipro, it makes me nausiated, and ethambutol which does the same thing. Unfortunatly, these effects are not enough to rule them out when it comes to treatment. Small histimine reactions, like itching and some inflamation are unpleasent, but the positive effects of the drug usually outweigh the discomfort. However, if she is having vision and hearing problems, anaphalactic reaction or difficult breathing, those are more serious. I'm on inhaled TOBI (tobra), and amakacin. They both make my chest tighten up, but a dose of albuterol makes if tolerable.
Her sensitivities may change as she gets older. I know it's hard to take meds that make you feel lousy and still believe that they are helping.
A note on the vest: I LOVE mine. I live alone and it makes it very easy to have effective therapy. YOur daughter may enjoy the sense of independence it gives. However, I believe that it is important to bond with your child through her treatment. If you are physically pounding on her back or sitting with her during nebs, it can really mean alot.

I hope something can be worked out so she is comfortable and getting the meds she needs.
Debbie
23w/cf

 

[Emily65Roses]

I hate both Cipro and Meropenem. I'm not allergic to either, but I don't like them much. Cipro usually doesn't work for me, and just tears through my intestines. And though it worked pretty well, the Meropenem kept me nauseous the whole two weeks I was on it.

 

[anonymous]

I'm allergic to cipro, ceftazadime, immepenum, aztreonam (and many more)....what kind of reaction does you daughter get from them?? I develop very large and itchy hives and they come on about 7-ish days after I start the meds. We did the same thing you did by stopping the med/tobra to rule out that it's not tobramycin. Now I get Desensatized to ceftazadime, meaning I recieve about 12 doses in a row of the med but the first dose is very dilluted, then each dose after that has more ceftaz in it. Finally by the 12th dose it's a full dose. Lately I've been hive free.
Email me if you have any questions,
Emily 22 pwcf letsrockcf@hotmail.com

 

[anonymous]

Its exactly the same reaction as you get and within the same time frame, but they are going to persist until the hives get too much for her to bear. She i has now got the pic line out so no more reactions until her next hospitalisation (hopefully that will be a while). She is only on small dose of Tobra at home and only when she is moist. I am amazed at the amount of meds most of the CFer's are on when I read some of the emails. I am also trying to get the Vest but have to wait until its approved in Aust, which could be another 10yrs or not even approved. Thanks for replying its good to know that their are other people out there with allergies to these drugs as so far Ash is the only one here that they know of here in Western Australia and not sure if anyone else in Aust is. We dont have chat rooms like this, apart from one in Victoria but its not used much so that is why I come on here, more people more help.
take care
paula
mom of Ash 11/wcf