Any info on the polyT 6T/9T variant?

B

Beofett

Guest
Hi all,<div><br></div><div>My 10 month son has been diagnosed with CF.  High-normal/low-borderline sweat tests, pancreatic sufficient.</div><div><br></div><div>The genetic testing revealed a single DF508 mutation, and the 6T/9T polyT variants.  The lab test indicated that the 6T variant was "likely to be clinically significant", which, in conjunction with the DF508 mutation, resulted in the diagnosis.</div><div><br>However, I have been able to find very little information on the 6T variant.  What little I found on the PolyT variants was generally linked to other mutations (such as the R117H), and most were discussing the 5T/7T/9T variants.</div><div><br>Can anyone point me in the direction of some resources for the 6T variant by itself, or in conjunction with single DF508?</div><div><br></div><div>Thanks</div>
 
B

Beofett

Guest
Hi all,<br>My 10 month son has been diagnosed with CF. High-normal/low-borderline sweat tests, pancreatic sufficient.<br>The genetic testing revealed a single DF508 mutation, and the 6T/9T polyT variants. The lab test indicated that the 6T variant was "likely to be clinically significant", which, in conjunction with the DF508 mutation, resulted in the diagnosis.<br>However, I have been able to find very little information on the 6T variant. What little I found on the PolyT variants was generally linked to other mutations (such as the R117H), and most were discussing the 5T/7T/9T variants.<br>Can anyone point me in the direction of some resources for the 6T variant by itself, or in conjunction with single DF508?<br>Thanks
 
B

Beofett

Guest
Hi all,<br>My 10 month son has been diagnosed with CF. High-normal/low-borderline sweat tests, pancreatic sufficient.<br>The genetic testing revealed a single DF508 mutation, and the 6T/9T polyT variants. The lab test indicated that the 6T variant was "likely to be clinically significant", which, in conjunction with the DF508 mutation, resulted in the diagnosis.<br>However, I have been able to find very little information on the 6T variant. What little I found on the PolyT variants was generally linked to other mutations (such as the R117H), and most were discussing the 5T/7T/9T variants.<br>Can anyone point me in the direction of some resources for the 6T variant by itself, or in conjunction with single DF508?<br>Thanks
 
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