Hello. I have actually done this a few times. Usually, I do it at the clinic, but if I am sick and I can't do it at my primary care physician's office, I do it at the lab. The last time I was at the lab, they gave me 3 or 4 sputum containers to take home (because I had been up there several times to do sputum's-they thought if they gave me extra it would be easier for me). If I have to do a sputum culture, then I can just do it here at home and then take it to the lab at the hospital. Hope that helps you!!