Do you take Pulmozyme? Do you have PA?

N

NoExcuses

New member
<b> A crossover, Randomized, Crontrolled Trial of Dornase Alfa before versus after physiotherapy in CF </b>

Fitzgerald, et al. PEDIATRICS Vol. 116 No. 4 October 2005, pp. e549-e554

Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF.

Patients who are colonized with PA may derive more improvement in FEV1 when dornase alfa is delivered after physiotherapy/PEP


<a target=_blank class=ftalternatingbarlinklarge href="http://pediatrics.aappublications.org/cgi/content/abstract/116/4/e549">http://pediatrics.aappublicati...nt/abstract/116/4/e549</a>
 
N

NoExcuses

New member
<b> A crossover, Randomized, Crontrolled Trial of Dornase Alfa before versus after physiotherapy in CF </b>

Fitzgerald, et al. PEDIATRICS Vol. 116 No. 4 October 2005, pp. e549-e554

Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF.

Patients who are colonized with PA may derive more improvement in FEV1 when dornase alfa is delivered after physiotherapy/PEP


<a target=_blank class=ftalternatingbarlinklarge href="http://pediatrics.aappublications.org/cgi/content/abstract/116/4/e549">http://pediatrics.aappublicati...nt/abstract/116/4/e549</a>
 
N

NoExcuses

New member
<b> A crossover, Randomized, Crontrolled Trial of Dornase Alfa before versus after physiotherapy in CF </b>

Fitzgerald, et al. PEDIATRICS Vol. 116 No. 4 October 2005, pp. e549-e554

Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF.

Patients who are colonized with PA may derive more improvement in FEV1 when dornase alfa is delivered after physiotherapy/PEP


<a target=_blank class=ftalternatingbarlinklarge href="http://pediatrics.aappublications.org/cgi/content/abstract/116/4/e549">http://pediatrics.aappublicati...nt/abstract/116/4/e549</a>
 
M

MOME2RT

New member
So if you dont culture PA & still take Pulmozyme should you do it BEFORE vest?

Just wondering, our CF team has always told us to do the Pulmoyme AFTER vest anyway. This is how RT does his meds: ALBEUTROL, VEST, PULMOZYME, if hes on TOBI, FLOVENT.

Yeah Amy thanks for all the info! <img src="i/expressions/face-icon-small-smile.gif" border="0">
 
M

MOME2RT

New member
So if you dont culture PA & still take Pulmozyme should you do it BEFORE vest?

Just wondering, our CF team has always told us to do the Pulmoyme AFTER vest anyway. This is how RT does his meds: ALBEUTROL, VEST, PULMOZYME, if hes on TOBI, FLOVENT.

Yeah Amy thanks for all the info! <img src="i/expressions/face-icon-small-smile.gif" border="0">
 
M

MOME2RT

New member
So if you dont culture PA & still take Pulmozyme should you do it BEFORE vest?

Just wondering, our CF team has always told us to do the Pulmoyme AFTER vest anyway. This is how RT does his meds: ALBEUTROL, VEST, PULMOZYME, if hes on TOBI, FLOVENT.

Yeah Amy thanks for all the info! <img src="i/expressions/face-icon-small-smile.gif" border="0">
 
N

NoExcuses

New member
as my original post said, Leah:

"Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF. "
 
N

NoExcuses

New member
as my original post said, Leah:

"Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF. "
 
N

NoExcuses

New member
as my original post said, Leah:

"Dornase alfa is equally efficacious when delivered before or after physiotherapy/PEP in patients with CF. "
 
C

consmom

New member
thanks for this info. I emailed my son's cf doc and asked him, he asked me to forward it as he was not aware of this study. We will try it if doc says ok as my son was pa + on last sputum culture. <img src="i/expressions/face-icon-small-sad.gif" border="0"> I had a hard time finding the forum but now I am glad. Thanks <img src="i/expressions/face-icon-small-happy.gif" border="0">
 
C

consmom

New member
thanks for this info. I emailed my son's cf doc and asked him, he asked me to forward it as he was not aware of this study. We will try it if doc says ok as my son was pa + on last sputum culture. <img src="i/expressions/face-icon-small-sad.gif" border="0"> I had a hard time finding the forum but now I am glad. Thanks <img src="i/expressions/face-icon-small-happy.gif" border="0">
 
C

consmom

New member
thanks for this info. I emailed my son's cf doc and asked him, he asked me to forward it as he was not aware of this study. We will try it if doc says ok as my son was pa + on last sputum culture. <img src="i/expressions/face-icon-small-sad.gif" border="0"> I had a hard time finding the forum but now I am glad. Thanks <img src="i/expressions/face-icon-small-happy.gif" border="0">
 
2

2perfectboys

Guest
I could see where pulmozyme may be better to use after vest. There are a few problems with this cited trial. Short duration, 2 weeks, and small sample size, only 52 subjects, which the reserchers acknowledged. They also stated "As a finding in a post hoc analysis, the result warrants additional investigation before it could be recommended as a therapeutic directive. " Prehaps there is a nother study that has since looked at this hypothesis or will in the near future.
 
2

2perfectboys

Guest
I could see where pulmozyme may be better to use after vest. There are a few problems with this cited trial. Short duration, 2 weeks, and small sample size, only 52 subjects, which the reserchers acknowledged. They also stated "As a finding in a post hoc analysis, the result warrants additional investigation before it could be recommended as a therapeutic directive. " Prehaps there is a nother study that has since looked at this hypothesis or will in the near future.
 
You must log in or register to reply here.
Top