Since entering the hospital the doctors have been treating my Mom vigorously with several antibiotics and interferon something...the change in her breathing and lung function has improved greatly. She will be released Monday, 5/28 on IV's and of course her 02 but her color was better today and she was almost back to her old self....it was so hard for her to miss Memorial Day Weekend in the campground, her 1st in 20 years but she was micro-managing via phone...that is how we are so sure she is BETTER. She will be taking it pretty easy for awhile but she will be home tomorrow, Monday, and we all can breathe alittle easier ourselves. I told her about all your good wishes and she said to say a "heartfelt Thank you".
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Greatbay update
- Thread starter greatbay
- Start date
Since entering the hospital the doctors have been treating my Mom vigorously with several antibiotics and interferon something...the change in her breathing and lung function has improved greatly. She will be released Monday, 5/28 on IV's and of course her 02 but her color was better today and she was almost back to her old self....it was so hard for her to miss Memorial Day Weekend in the campground, her 1st in 20 years but she was micro-managing via phone...that is how we are so sure she is BETTER. She will be taking it pretty easy for awhile but she will be home tomorrow, Monday, and we all can breathe alittle easier ourselves. I told her about all your good wishes and she said to say a "heartfelt Thank you".
Since entering the hospital the doctors have been treating my Mom vigorously with several antibiotics and interferon something...the change in her breathing and lung function has improved greatly. She will be released Monday, 5/28 on IV's and of course her 02 but her color was better today and she was almost back to her old self....it was so hard for her to miss Memorial Day Weekend in the campground, her 1st in 20 years but she was micro-managing via phone...that is how we are so sure she is BETTER. She will be taking it pretty easy for awhile but she will be home tomorrow, Monday, and we all can breathe alittle easier ourselves. I told her about all your good wishes and she said to say a "heartfelt Thank you".
kayleesgrandma
New member
Wow, God was really busy this weekend! Thank God, for good news. Please tell her how much everyone is thinking of her! <img src="i/expressions/heart.gif" border="0">
kayleesgrandma
New member
Wow, God was really busy this weekend! Thank God, for good news. Please tell her how much everyone is thinking of her! <img src="i/expressions/heart.gif" border="0">
kayleesgrandma
New member
Wow, God was really busy this weekend! Thank God, for good news. Please tell her how much everyone is thinking of her! <img src="i/expressions/heart.gif" border="0">
L
luke
Guest
interferon, I am interested. Do you know why they gave it?
L
luke
Guest
interferon, I am interested. Do you know why they gave it?
L
luke
Guest
interferon, I am interested. Do you know why they gave it?
Absolutely...my friend in the Netherlands told me about it because his docs have him on it to treat m. abscessus...a particularly nasty mycobacterium that I have as well. So after learning about it from him...I began really researching its use in cf as well.
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!
Absolutely...my friend in the Netherlands told me about it because his docs have him on it to treat m. abscessus...a particularly nasty mycobacterium that I have as well. So after learning about it from him...I began really researching its use in cf as well.
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!
Absolutely...my friend in the Netherlands told me about it because his docs have him on it to treat m. abscessus...a particularly nasty mycobacterium that I have as well. So after learning about it from him...I began really researching its use in cf as well.
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!
Gamma Interferon is the chemical that turns on the macrophages (killer defence cells) to kill intracellular mycobacteria, virus and parasites. Pseudo is an extracellular bacteria...interestingly though, a by product of pseudo actually inactivates gamma interferon in the cf lung. Another reason why our immune response is crippled to invaders.
Healthy cfers have normal amounts of IFN gamma (gamma interferon) in their systems.... This means they are experiencing a T(h)1 response in the immune sytem...a fighting response with very little inflammation. Of course, when cfers start culturing more bugs and experiencing more problems their immune sytems become burdered...and here is where the problems start. A switch to T(h)2 which is characterized by low IFN gamma and high inflammatory markers in the blood and sputum. Recent research suggests that zithromax is so crucial in cf because it is an anti-inflammatory and it modulates the immune response by increasing IFN gamma and switches the body from a T(h)2 response to a (T)h 1....our fighting system. Interestingly, research also shows that zithromax and biaxin (clarythromicin) are good prophylaxis against mycobacterium because they raise IFN gamma thereby protecting the "host"
There is a ton of research out there that state those with multi drug resistant mycos respond to therapy if IFN gamma is added. Some actually clear the organism while others are able to stabilzie with no further loss of lung function. Other research shows that cfers who are simply colonized have almost normal IFN gamma vs. those who have active disease....they all have very low IFN gamma.
In 2004, Stanford conducted a trial of inhaled IFN gamma for cfers. They tested it on healthy cfers who did not culture any of the mycos.... Of course, their was no change in lung function, bacterial load (pseudo) or inflammatory markers. Two reasons for this.....they didn't take it long enough and the main one...THEY TESTED THE WRONG GROUP OF CFERS.
Most research suggests that mycos are first cultured after long term steroid therapy. Steroids suppress both the T(h) 1 and the T(h) 2 responses....for whatever reason, after steroid therapy your body cannot regain the IFN gamma without help. Although, that is not always the case...just the trend.
Recent studies in cf also indicate that probiotics are a useful tool in the fight against inflammation in cf.... Interestingly, research shows that lactobascillus GG actually increases IFN gamma in VIVO (in the person) and turns on the T(h)1 response.
It is so important to keep your weight up and eat healthy. Nutritional status is DIRECTLY correlated to IFN gamma production!!!