I have yet to need to go on meds for it, but they've told me at least once that my liver is "enlarged and inflamed." Like it gets irritated from time to time, but it's not failing or anything. It was enough for them to tell me to almost stop drinking altogether for a few weeks, though. And it's not as if I'm an alcoholic. I don't drink that much or that often, but they wanted to give my liver a break. I was instructed not to drink, and if I did, to stick to beer malt liquor, or wine coolers, as opposed to hard liquor.