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Resistance to Antibiotics
- Thread starter anonymous
- Start date
thelizardqueen
New member
Its the bacteria that becomes resistant to the antibiotics. If you keep using the same med over and over and over to treat an infection, the bacteria will finally become wise, and sort of mutate so that the antibiotic won't work. That's my understanding anyway. Its like your bacteria becomes stronger against whatever med you're repeatidly using. That's why I don't agree with regular tuneups when you don't need them. That's also why when I'm on TOBI, I'm one month on, one month off, so that my bacteria doesn't get used to it.
when you take an antibiotic, 100% of the bacteria aren't elminated. ever. there may just be one remaining bacteria, a single cell, that had a mutation that allowed it to survive the antibiotic you gave it. let's use PA, for example.
so you have a single cell of PA. for whatever reason, you PA is given the opportunity to reproduce (you got a cold, you weren't compliant with your meds, you were dehydrated after flying, stress from work is wearing you down) and now instead of 1 cell of PA you have 50. They're all identical because bacteria asexually reproduce.
So now you have 50 PA cells that stemmed from that original PA cell that wasn't killed off by the antibiotic. So these 50 bacteria now have resistance to the antibiotic.
Of course, this is a simplified example of resistance, but fundamentally, this is how resistance occurs.
And this is why it's SO VERY IMPORTANT that each and every one of us is compliant with our antibiotics. Whether it's taking Cipro as directed, or not missing a single day of TOBI when you're on cycle.
There are only so many antibiotics out there that work for virulent bacteria such as PA. And pharmaceutical companies aren't developing any more because peope expect antibiotics to have zero side effects. So drug companies are working more towards lifestyle meds, rather than life-savers.
so you have a single cell of PA. for whatever reason, you PA is given the opportunity to reproduce (you got a cold, you weren't compliant with your meds, you were dehydrated after flying, stress from work is wearing you down) and now instead of 1 cell of PA you have 50. They're all identical because bacteria asexually reproduce.
So now you have 50 PA cells that stemmed from that original PA cell that wasn't killed off by the antibiotic. So these 50 bacteria now have resistance to the antibiotic.
Of course, this is a simplified example of resistance, but fundamentally, this is how resistance occurs.
And this is why it's SO VERY IMPORTANT that each and every one of us is compliant with our antibiotics. Whether it's taking Cipro as directed, or not missing a single day of TOBI when you're on cycle.
There are only so many antibiotics out there that work for virulent bacteria such as PA. And pharmaceutical companies aren't developing any more because peope expect antibiotics to have zero side effects. So drug companies are working more towards lifestyle meds, rather than life-savers.
Thanks for all your replies. My daughter cultured Pseudo when she was 10 months old, then cultured again almost a year later. She has been nebbing Colomycin since last October. Does this seem about right to you?
Grateful for any advice.
Thanks.
Charlotte<img src="i/expressions/face-icon-small-confused.gif" border="0">
Grateful for any advice.
Thanks.
Charlotte<img src="i/expressions/face-icon-small-confused.gif" border="0">
sounds right to me - you are outside the US, i think, where colomycin is used more frequently than TOBi because it is cheaper. Colomycin will kill Pseudo. Just don't skip treatments and breath deeply <img src="i/expressions/face-icon-small-smile.gif" border="0"> <img src="i/expressions/face-icon-small-smile.gif" border="0"> <img src="i/expressions/face-icon-small-smile.gif" border="0">