Hmm, a good question.
I am replying as a PWCF. I never did homeschooling, but also never had many problems growing up as far as hospitalizations either. I did have a couple times where accomadations were needed, but never had any problems though, but I did live in a small town, with only one high school, one junior high and middle school and 3 elementary schools.
Being around other kids is definitely a risk, but can also help build immunities up also. As your kids age, they can hopefully start doing extra curricular activities which can help them stay active and feel part of a team. I did cheerleading and it was a great form of exercise. I know many cf'ers that did sports growing up on the forums too that would most likely attest to the benefit of being an athlete. I also did choir which is another form of lung exercise just like playing an instrument that you blow into could be.
I know some religious friends that did homeschooling at a younger age, then started in either 8th or 9th grade at public school, and maybe you could start like that to help out during the "taste everything, snotty noses, not washing hands unless told so" stage?
I thought it might help to give you one view of a cf'er. Good Luck in deciding, whenever that is <img src="i/expressions/face-icon-small-smile.gif" border="0">