A novel approach to fight PA infections in the lungs of people with CF is being tested in a new pilot study in the UK. Volunteers with CF will be given capsules of either garlic extract or placebo (olive oil) for 2 months and teh levels of bacteria in their sputum will be measured.
The potential of garlic extract as an antipseudomonal agent was supported by the results of a study conducted in Denmark. In that study, exposure of PA to garlic extract made the bacteria more sensitive to tobramycin and to immune defense system cells. The garlic extract also provided mice with more significant protection from PA lung infections.
Safety of the extract will be examined in addition to any potentially positive effects on weight and lung function
<a target=_blank class=ftalternatingbarlinklarge href="http://www.cff.org/aboutCFFoundation/NewsEvents/index.cfm?ID=5814&TYPE=1670">http://www.cff.org/aboutCFFoun....cfm?ID=5814&TYPE=1670</a>
The potential of garlic extract as an antipseudomonal agent was supported by the results of a study conducted in Denmark. In that study, exposure of PA to garlic extract made the bacteria more sensitive to tobramycin and to immune defense system cells. The garlic extract also provided mice with more significant protection from PA lung infections.
Safety of the extract will be examined in addition to any potentially positive effects on weight and lung function
<a target=_blank class=ftalternatingbarlinklarge href="http://www.cff.org/aboutCFFoundation/NewsEvents/index.cfm?ID=5814&TYPE=1670">http://www.cff.org/aboutCFFoun....cfm?ID=5814&TYPE=1670</a>