Regarding these drugs, particularly Kalydeco in combo with VX-809, and Kalydeco in combo with VX-661, I understand that they improve lung function. One drug acting as a potentiator, the other a corrector allowing NaCl to reach the surface of the cell and correcting the problem of sticky mucus. Is it safe to assume that it's affecting all cells, therefore all systems affected by sticky mucus will benefit? Specifically the pancreas. Assuming there is no damage to the organ or the duct, will blockages clear and function return to normal? Has anyone in trials experienced this?