You're welcome. The article I attached that it came from does explain that medicine is lost when you use some of these devices and it appears to say that the Pari device does not lose the medicine - although the article is a bit difficult to read. The article says that if you are using a PEP/nebulizer combo to do medicines such as Pulmozyme that this can mean you don't get the right dose as quite a bit of medicine is lost.
In the diagram, you'll see that the delivery of the LCPlus nebulizer is at the same level whether or not the Pari-Pep or Pari-Pep S (a different model) is used. It shows how much is lost (apparently no more than if you used just the nebulizer) at two different resistance settings (the little holes in the device that set the pressure in the Positive expiratory pressure device).
I have used the Pari-Pep and I like it better than the flutter. I can't say that I have used it with my nebulizer, but alone as a Pari-Pep device. I asked a respiratory therapist which device patients preferred and this is what she recommended. If you're travelling and you want a few to sterilize, they are inexpensive enough to get a few. I tend to agree with the other posters here that for a trip of 5 days or so, or even up to a week, a smaller device is nicer to bring. But after that, I'm looking forward to my vest again. When travelling, I do my pari-pep, then do my hypertonic saline. In the evening, I sterilize all the devices and air dry them on paper towels I bring with me. A key part of using Pari-Pep is having the respiratory therapist train you, so you are doing this comfortably, getting as much out as you can, without making yourself uncomfortable. They can also suggest the best resistance setting for you to use on the device and watch your technique.
Another thing I have used from time-to-time, when I don't want to bring a vest, is a massage percussor. I generally throw this in my carry-on, but have sometimes packed it in my luggage (if I've got another device with me). The vibration from the massager does thin the mucous, but you have to be careful when you use it, not to hit bony parts and keep the setting pretty low. There are more professional models specifically for chest diseases ->
http://www.protherapysupplies.com/Shop-By-Category/Electrical/G5-Flimm-Fighter-Massage-Percussor and this one which Jerry Cahill also reviews
http://www.medsystems.com/professional/cystic-fibrosis-therapy/
This is the one I used until it got fried by a flakey outlet in a place where I was visiting
http://www.everydaycomfort.com/homedics-pa-100-therapist-select-percussion-action-massager/ . The benefit of taking an inexpensive device like this was "no worries" if it gets fried or smashed up in your luggage.
Taking a massager of some type and a pari-pep is the option I prefer. Pari-pep works well and if you find yourself longing for your vest, because you can feel something that you can't quite get out, you can use the massager to get at those areas. And I really don't say anything to TSA about the massager. They look at it and go "uh-huh" and put it back in the bag. I do keep my meds in a plastic bag in the bin and the Pari-Pep in my purse.