We adopted both our daughters. (I have CF DDF508 and husband is clear of the major mutations) Our eldest (now 10) was adopted at age 11 months from Azerbaijan. Our youngest daughter, now 5.5) was adopted as a newborn domestically from CA. The domestic adoption was by far the quickest and easiest, took us about 3 weeks. Yes, the CF was an issue, but I had a doctors letter in my file, we had a tight knit support structure, backup plans, and were in a good place financially. More importantly, we had a whole lot of love and opportunities to offer a child. A lot of people were willing to step forward and say we'd make terrific parents. Our kiddos are amazing, both whips in school and competitive gymnasts. Interestingly, our youngest daughters bio uncle has CF. DD tested clean at the newborn screen, but my guess is that she is a carrier.