This one is news to me, but I bet it's old news to you guys. The weird thing, is it's not listed on the CF drug dev pipeline. It's made from Mannitol, a naturally occuring sugar. I'm just curious if you guys know anything about it. Anytime there is a new drug coming for us, it's good news.
BTW when the docs assistant was discussing my ct scan results with me, she mentioned I had an area of Bronchiectasis, and that was a first and kind of bummed me out. So I started doing a little reading, and found this drug to treat it and overall treat CF. It seems so far, this drug has showed amazing results in CF patients. Heres the link:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.pharmaxis.com.au/pharmaxis/index.cfm?1395DF0D-AB0D-736C-4E53-C6A7359293B4#bronchitol
">http://www.pharmaxis.com.au/ph...A7359293B4#bronchitol
</a>
Bronchitoltm
Bronchitoltm is a new approach to the management of chronic obstructive lung diseases such as COPD [link to COPD in respiratory disease section] and cystic fibrosis [link to cystic fibrosis in respiratory disease section], which share a common problem of abnormal production and ineffective clearance of mucus in the lungs.Bronchitoltm aims to restore the ability of patients' lungs to clear mucus by promoting salt and water movement through airway cells.
Bronchitoltm is produced form a naturally occurring sugar called mannitol. The mannitol is formulated into a dry powder with a particle size small enough to allow patients to breathe it into their lungs from a simple inhaler.There is no need for the use of nebulisers.
Bronchitoltm is thought to increase mucus clearance by the following mechanisms:
* It changes the viscosity of mucus, making it easier to clear
* It mimics the action of salt in healthy lungs to draw water out of the cells and into the airway surface liquid
* The restored airway surface liquid and a direct action on the cilia themselves cause an increase in cilia effectiveness
* It stimulates cough
The net result for patients taking Bronchitoltm is expected to be:
* improved mucus clearance;
* longer cough-free periods;
* improved lung performance; and,
* fewer infections.
I'm sure this is old news to others here, but I generally look to the cff drug pipeline to see whats coming, and this wasn't on it.
Also, any word on Denusofol and Aztreonam? I looked at the expanded access page for the Aztreonam drug, and even with 1000 miles distance put into the search field for looking for a nearbye participating site, it said there weren't any. Not sure if that means it's not in the US or what.
Anyways i'm really looking forward to these 3 new drugs. If you know about any of them to any degree, please share. I'd like to get on den and aztreonam as soon as possible, so if I have Bronchiectasis, I want to make sure it doesn't spread. Maybe this is what was behind my chronic bleeds <img src="i/expressions/face-icon-small-sad.gif" border="0">
I wish I had the time to sit around and be all detective on this stuff, but due to work, I just don't have the time anymore.
BTW when the docs assistant was discussing my ct scan results with me, she mentioned I had an area of Bronchiectasis, and that was a first and kind of bummed me out. So I started doing a little reading, and found this drug to treat it and overall treat CF. It seems so far, this drug has showed amazing results in CF patients. Heres the link:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.pharmaxis.com.au/pharmaxis/index.cfm?1395DF0D-AB0D-736C-4E53-C6A7359293B4#bronchitol
">http://www.pharmaxis.com.au/ph...A7359293B4#bronchitol
</a>
Bronchitoltm
Bronchitoltm is a new approach to the management of chronic obstructive lung diseases such as COPD [link to COPD in respiratory disease section] and cystic fibrosis [link to cystic fibrosis in respiratory disease section], which share a common problem of abnormal production and ineffective clearance of mucus in the lungs.Bronchitoltm aims to restore the ability of patients' lungs to clear mucus by promoting salt and water movement through airway cells.
Bronchitoltm is produced form a naturally occurring sugar called mannitol. The mannitol is formulated into a dry powder with a particle size small enough to allow patients to breathe it into their lungs from a simple inhaler.There is no need for the use of nebulisers.
Bronchitoltm is thought to increase mucus clearance by the following mechanisms:
* It changes the viscosity of mucus, making it easier to clear
* It mimics the action of salt in healthy lungs to draw water out of the cells and into the airway surface liquid
* The restored airway surface liquid and a direct action on the cilia themselves cause an increase in cilia effectiveness
* It stimulates cough
The net result for patients taking Bronchitoltm is expected to be:
* improved mucus clearance;
* longer cough-free periods;
* improved lung performance; and,
* fewer infections.
I'm sure this is old news to others here, but I generally look to the cff drug pipeline to see whats coming, and this wasn't on it.
Also, any word on Denusofol and Aztreonam? I looked at the expanded access page for the Aztreonam drug, and even with 1000 miles distance put into the search field for looking for a nearbye participating site, it said there weren't any. Not sure if that means it's not in the US or what.
Anyways i'm really looking forward to these 3 new drugs. If you know about any of them to any degree, please share. I'd like to get on den and aztreonam as soon as possible, so if I have Bronchiectasis, I want to make sure it doesn't spread. Maybe this is what was behind my chronic bleeds <img src="i/expressions/face-icon-small-sad.gif" border="0">
I wish I had the time to sit around and be all detective on this stuff, but due to work, I just don't have the time anymore.