As long as you have safe sex, there's no problem. At least that's what I've found. My FEV1 is somewhere in the lower fifties to upper fourties, and I have no problem doing 'the deed', even though sometimes I do get short of breath. As far as an orgasm...without getting too personal, I've never had an issue with it, and I imagine it's the same as any other 'normal' woman's. I usually have a short coughing fit afterwards because of the strain on my body, but other than that, no issues. The only advice I can offer is to do your therapy beforehand (if possible) to make it easier on yourself. If you can't do the whole thing, take a puff from an albuterol inhaler to open up your lungs. Plus, it's a good workout, so don't be afraid to try it. Heck, it might actually HELP your lung function instead of hurting it!