As I've said before it's best to consult your doctor regarding any of this stuff.
Kiel, question, are you going to take acetyl-CoA as well, just curious.
Regarding Acetylcholine which that list talked about:
<i>"Acetylcholine, often abbreviated as ACh, was the first neurotransmitter to be identified. It is a chemical transmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.
Acetylcholine is synthesized in certain neurons by the enzyme choline acetyltransferase from the compounds <b>choline</b> and <b>acetyl-CoA</b>. Organic mercurial compounds have a high affinity for sulfhydryl groups, which attributes to its effect on enzyme dysfunction of choline acetyl transferase. This inhibition may lead to acetylcholine deficiency, and can have consequences on motor function.
Normally, the enzyme acetylcholinesterase converts acetylcholine into the inactive metabolites choline and acetate. The devastating effects of nerve agents (in bioterrorism, Sarin gas for example) are due to their inhibition of this enzyme, resulting in continuous stimulation of the muscles, glands and central nervous system. Certain insecticides are effective because they inhibit this enzyme in insects. On the other hand, since a shortage of acetylcholine in the brain has been associated with Alzheimer's disease, some drugs that inhibit acetylcholinesterase are used in the treatment of that disease."</i>
Here are some pages for Choline:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.abc.net.au/rn/talks...ies/s119524.htm
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<br ">http://www.abc.net.au/rn/talks...s119524.htm
</a></a>
<a target=_blank class=ftalternatingbarlinklarge href="http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/cho_0283.shtml
<br ">">http://www.pdrhealth.com/dru.../cho_0283.shtml
</a>
'The foods richest in phosphatidylcholine -- the major delivery form of <b>choline</b> -- are beef liver, egg yolks and soya. Beef liver, iceberg lettuce, peanut butter, peanuts, sunflower seeds, and cauliflower are some foods that contain free choline.'
Acetylcholine is synthesized basically by an enzyme made up of choline and acetyl-CoA. You get choline from a number of natural things in a healthy diet.
Now onto acetyl-CoA
<i>"it contributes an acetyl group to choline to produce acetylcholine, in a reaction catalysed by choline acetyltransferase. Its main task is conveying the carbon atoms within the acetyl group to the citric acid cycle to be oxidized for energy production.
Coenzyme A is very central to the balance between carbohydrate metabolism and fat metabolism. Normally, acetyl-CoA from fatty acid metabolism feeds into the citric acid cycle, contributing to the cell's energy supply. In the liver, when levels of circulating fatty acids are high, the production of acetyl-CoA from fat breakdown exceeds the cellular energy requirements. To make use of the energy available from the excess acetyl-CoA, ketone bodies are produced which can then circulate in the blood.
In some circumstances this can lead to an excess of ketone bodies in the blood, a condition known as ketosis. This can occur in diabetes, starvation or in people following low-carbohydrate diets, all of which can cause fats to be metabolised as a major source of energy."</i>
