Cipro and Levofloxacin Side Effects...

dasjsmum

New member
Children under about 18 aren't given Cipro here in Australia (at least in my clinic).

That's because there is evidence it can affect the bones as they grow, so it isnt given until later teenage years. Granted, there may be times where it is administered to younger children, but none of mine have had it until they were older.

We have two sets of nebulised antibiotics to administer instead, Tobramycin and Timentin, twice daily.
 

dasjsmum

New member
Children under about 18 aren't given Cipro here in Australia (at least in my clinic).

That's because there is evidence it can affect the bones as they grow, so it isnt given until later teenage years. Granted, there may be times where it is administered to younger children, but none of mine have had it until they were older.

We have two sets of nebulised antibiotics to administer instead, Tobramycin and Timentin, twice daily.
 

dasjsmum

New member
Children under about 18 aren't given Cipro here in Australia (at least in my clinic).

That's because there is evidence it can affect the bones as they grow, so it isnt given until later teenage years. Granted, there may be times where it is administered to younger children, but none of mine have had it until they were older.

We have two sets of nebulised antibiotics to administer instead, Tobramycin and Timentin, twice daily.
 

dasjsmum

New member
Children under about 18 aren't given Cipro here in Australia (at least in my clinic).

That's because there is evidence it can affect the bones as they grow, so it isnt given until later teenage years. Granted, there may be times where it is administered to younger children, but none of mine have had it until they were older.

We have two sets of nebulised antibiotics to administer instead, Tobramycin and Timentin, twice daily.
 

dasjsmum

New member
Children under about 18 aren't given Cipro here in Australia (at least in my clinic).

That's because there is evidence it can affect the bones as they grow, so it isnt given until later teenage years. Granted, there may be times where it is administered to younger children, but none of mine have had it until they were older.

We have two sets of nebulised antibiotics to administer instead, Tobramycin and Timentin, twice daily.
 

NoExcuses

New member
the problem with nebulized antibiotics is that mucus can block these nebbed meds from reaching the infection site. If you have a bunch of mucus in the airways blocking the site of the infection, the tobramycin or timentin won't reach the site of the infection and therefore won't be affective.

something systemic such as PO abx (cipro) or IV abx is that nothing can block their way in reaching the infection site.

thousands of CF patients have been given cipro as children in the US and widespread issues certainly don't occur. but certainly side effects do occur - it's just a matter of which abx you have at your disposal versus how proactive you want to be with treating PA. check out denmark - you get a more side-effect heavy antibiotic (tobramycin..... MUCH MUCH MUCH more riddled with side effects than cipro) every 3 months prophylacticly. CF patients in Denmark have an average life expectancy well into their 50s.
 

NoExcuses

New member
the problem with nebulized antibiotics is that mucus can block these nebbed meds from reaching the infection site. If you have a bunch of mucus in the airways blocking the site of the infection, the tobramycin or timentin won't reach the site of the infection and therefore won't be affective.

something systemic such as PO abx (cipro) or IV abx is that nothing can block their way in reaching the infection site.

thousands of CF patients have been given cipro as children in the US and widespread issues certainly don't occur. but certainly side effects do occur - it's just a matter of which abx you have at your disposal versus how proactive you want to be with treating PA. check out denmark - you get a more side-effect heavy antibiotic (tobramycin..... MUCH MUCH MUCH more riddled with side effects than cipro) every 3 months prophylacticly. CF patients in Denmark have an average life expectancy well into their 50s.
 

NoExcuses

New member
the problem with nebulized antibiotics is that mucus can block these nebbed meds from reaching the infection site. If you have a bunch of mucus in the airways blocking the site of the infection, the tobramycin or timentin won't reach the site of the infection and therefore won't be affective.

something systemic such as PO abx (cipro) or IV abx is that nothing can block their way in reaching the infection site.

thousands of CF patients have been given cipro as children in the US and widespread issues certainly don't occur. but certainly side effects do occur - it's just a matter of which abx you have at your disposal versus how proactive you want to be with treating PA. check out denmark - you get a more side-effect heavy antibiotic (tobramycin..... MUCH MUCH MUCH more riddled with side effects than cipro) every 3 months prophylacticly. CF patients in Denmark have an average life expectancy well into their 50s.
 

NoExcuses

New member
the problem with nebulized antibiotics is that mucus can block these nebbed meds from reaching the infection site. If you have a bunch of mucus in the airways blocking the site of the infection, the tobramycin or timentin won't reach the site of the infection and therefore won't be affective.

something systemic such as PO abx (cipro) or IV abx is that nothing can block their way in reaching the infection site.

thousands of CF patients have been given cipro as children in the US and widespread issues certainly don't occur. but certainly side effects do occur - it's just a matter of which abx you have at your disposal versus how proactive you want to be with treating PA. check out denmark - you get a more side-effect heavy antibiotic (tobramycin..... MUCH MUCH MUCH more riddled with side effects than cipro) every 3 months prophylacticly. CF patients in Denmark have an average life expectancy well into their 50s.
 

NoExcuses

New member
the problem with nebulized antibiotics is that mucus can block these nebbed meds from reaching the infection site. If you have a bunch of mucus in the airways blocking the site of the infection, the tobramycin or timentin won't reach the site of the infection and therefore won't be affective.

something systemic such as PO abx (cipro) or IV abx is that nothing can block their way in reaching the infection site.

thousands of CF patients have been given cipro as children in the US and widespread issues certainly don't occur. but certainly side effects do occur - it's just a matter of which abx you have at your disposal versus how proactive you want to be with treating PA. check out denmark - you get a more side-effect heavy antibiotic (tobramycin..... MUCH MUCH MUCH more riddled with side effects than cipro) every 3 months prophylacticly. CF patients in Denmark have an average life expectancy well into their 50s.
 

Foody

New member
I think was surprised most was that an antibiotic could have this type of affect on the body when, at least in my mind, I've always thought them to be fairly benign. I was most surprised that it is prescribed so much for simple otitus media and UTI's in children in this country when it is really meant to be a last resort abx. I am not aware of the studies on which abx are useful in PA overgrowth and assumed TOBI was the main one, so I get the importance of it in infections which won't go away or rare cases. I just wouldn't want my child on it as a first line of defense with it's high rate of adverse reactions and the joint/tendon/bone research. Australia is not the only country who will not prescribe it for children under 18; some are suggesting that our doctors in the US are overzealous with it and put children at risk because of it. Public Citizen has just sued the FDA (1/3/08) over the tendon rupture issues <a target=_blank class=ftalternatingbarlinklarge href="http://www.citizen.org/pressroom/release.cfm?ID=2581
">http://www.citizen.org/pressroom/release.cfm?ID=2581
</a>
Amy, couldn't agree more about misuse of antibiotics and the risk to children with or without CF.
 

Foody

New member
I think was surprised most was that an antibiotic could have this type of affect on the body when, at least in my mind, I've always thought them to be fairly benign. I was most surprised that it is prescribed so much for simple otitus media and UTI's in children in this country when it is really meant to be a last resort abx. I am not aware of the studies on which abx are useful in PA overgrowth and assumed TOBI was the main one, so I get the importance of it in infections which won't go away or rare cases. I just wouldn't want my child on it as a first line of defense with it's high rate of adverse reactions and the joint/tendon/bone research. Australia is not the only country who will not prescribe it for children under 18; some are suggesting that our doctors in the US are overzealous with it and put children at risk because of it. Public Citizen has just sued the FDA (1/3/08) over the tendon rupture issues <a target=_blank class=ftalternatingbarlinklarge href="http://www.citizen.org/pressroom/release.cfm?ID=2581
">http://www.citizen.org/pressroom/release.cfm?ID=2581
</a>
Amy, couldn't agree more about misuse of antibiotics and the risk to children with or without CF.
 

Foody

New member
I think was surprised most was that an antibiotic could have this type of affect on the body when, at least in my mind, I've always thought them to be fairly benign. I was most surprised that it is prescribed so much for simple otitus media and UTI's in children in this country when it is really meant to be a last resort abx. I am not aware of the studies on which abx are useful in PA overgrowth and assumed TOBI was the main one, so I get the importance of it in infections which won't go away or rare cases. I just wouldn't want my child on it as a first line of defense with it's high rate of adverse reactions and the joint/tendon/bone research. Australia is not the only country who will not prescribe it for children under 18; some are suggesting that our doctors in the US are overzealous with it and put children at risk because of it. Public Citizen has just sued the FDA (1/3/08) over the tendon rupture issues <a target=_blank class=ftalternatingbarlinklarge href="http://www.citizen.org/pressroom/release.cfm?ID=2581
">http://www.citizen.org/pressroom/release.cfm?ID=2581
</a>
Amy, couldn't agree more about misuse of antibiotics and the risk to children with or without CF.
 

Foody

New member
I think was surprised most was that an antibiotic could have this type of affect on the body when, at least in my mind, I've always thought them to be fairly benign. I was most surprised that it is prescribed so much for simple otitus media and UTI's in children in this country when it is really meant to be a last resort abx. I am not aware of the studies on which abx are useful in PA overgrowth and assumed TOBI was the main one, so I get the importance of it in infections which won't go away or rare cases. I just wouldn't want my child on it as a first line of defense with it's high rate of adverse reactions and the joint/tendon/bone research. Australia is not the only country who will not prescribe it for children under 18; some are suggesting that our doctors in the US are overzealous with it and put children at risk because of it. Public Citizen has just sued the FDA (1/3/08) over the tendon rupture issues <a target=_blank class=ftalternatingbarlinklarge href="http://www.citizen.org/pressroom/release.cfm?ID=2581
">http://www.citizen.org/pressroom/release.cfm?ID=2581
</a>
Amy, couldn't agree more about misuse of antibiotics and the risk to children with or without CF.
 

Foody

New member
I think was surprised most was that an antibiotic could have this type of affect on the body when, at least in my mind, I've always thought them to be fairly benign. I was most surprised that it is prescribed so much for simple otitus media and UTI's in children in this country when it is really meant to be a last resort abx. I am not aware of the studies on which abx are useful in PA overgrowth and assumed TOBI was the main one, so I get the importance of it in infections which won't go away or rare cases. I just wouldn't want my child on it as a first line of defense with it's high rate of adverse reactions and the joint/tendon/bone research. Australia is not the only country who will not prescribe it for children under 18; some are suggesting that our doctors in the US are overzealous with it and put children at risk because of it. Public Citizen has just sued the FDA (1/3/08) over the tendon rupture issues <a target=_blank class=ftalternatingbarlinklarge href="http://www.citizen.org/pressroom/release.cfm?ID=2581
">http://www.citizen.org/pressroom/release.cfm?ID=2581
</a>
Amy, couldn't agree more about misuse of antibiotics and the risk to children with or without CF.
 

Ratatosk

Administrator
Staff member
I do recall when DS first cultured pseudo and enterbacter cochlae at 2-3 months and had a horrible junky cough, and was put on tobi and septra, DS developed a rash and we thought he might be allergic to septra. His doctor mentioned that he was concerned if he was allergic because that ruled out a number of antibiotics they could use on him and he didn't want to start him on cipro due to issues with it affecting cartiledge (sp) on such a small child. Turns out he wasn't allergic, but the cipro comment stuck in my head and years later when he was put on it, it made me a little (lot) nervous.
 

Ratatosk

Administrator
Staff member
I do recall when DS first cultured pseudo and enterbacter cochlae at 2-3 months and had a horrible junky cough, and was put on tobi and septra, DS developed a rash and we thought he might be allergic to septra. His doctor mentioned that he was concerned if he was allergic because that ruled out a number of antibiotics they could use on him and he didn't want to start him on cipro due to issues with it affecting cartiledge (sp) on such a small child. Turns out he wasn't allergic, but the cipro comment stuck in my head and years later when he was put on it, it made me a little (lot) nervous.
 

Ratatosk

Administrator
Staff member
I do recall when DS first cultured pseudo and enterbacter cochlae at 2-3 months and had a horrible junky cough, and was put on tobi and septra, DS developed a rash and we thought he might be allergic to septra. His doctor mentioned that he was concerned if he was allergic because that ruled out a number of antibiotics they could use on him and he didn't want to start him on cipro due to issues with it affecting cartiledge (sp) on such a small child. Turns out he wasn't allergic, but the cipro comment stuck in my head and years later when he was put on it, it made me a little (lot) nervous.
 

Ratatosk

Administrator
Staff member
I do recall when DS first cultured pseudo and enterbacter cochlae at 2-3 months and had a horrible junky cough, and was put on tobi and septra, DS developed a rash and we thought he might be allergic to septra. His doctor mentioned that he was concerned if he was allergic because that ruled out a number of antibiotics they could use on him and he didn't want to start him on cipro due to issues with it affecting cartiledge (sp) on such a small child. Turns out he wasn't allergic, but the cipro comment stuck in my head and years later when he was put on it, it made me a little (lot) nervous.
 

Ratatosk

Administrator
Staff member
I do recall when DS first cultured pseudo and enterbacter cochlae at 2-3 months and had a horrible junky cough, and was put on tobi and septra, DS developed a rash and we thought he might be allergic to septra. His doctor mentioned that he was concerned if he was allergic because that ruled out a number of antibiotics they could use on him and he didn't want to start him on cipro due to issues with it affecting cartiledge (sp) on such a small child. Turns out he wasn't allergic, but the cipro comment stuck in my head and years later when he was put on it, it made me a little (lot) nervous.
 
Top