Colistin while PG?

K

Kristen

New member
I am currently on inhaled colistin one month on, one month off. My CF doctor said it is safe to take during pregnancy because "the molecules are too large to pass from the lungs to the blood stream."

However, I have since read a journal article that took blood samples from patients after they inhaled colistin, and some did make it to their bloodstream. The amount was much lower than if they had taken it "systemically" (which I assume means via IV?). But still, now I am concerned.

Has anyone else talked to her doctor about taking colistin during pregnancy? If so, what did the doctor say?
 
K

Kristen

New member
I am currently on inhaled colistin one month on, one month off. My CF doctor said it is safe to take during pregnancy because "the molecules are too large to pass from the lungs to the blood stream."

However, I have since read a journal article that took blood samples from patients after they inhaled colistin, and some did make it to their bloodstream. The amount was much lower than if they had taken it "systemically" (which I assume means via IV?). But still, now I am concerned.

Has anyone else talked to her doctor about taking colistin during pregnancy? If so, what did the doctor say?
 
K

Kristen

New member
I am currently on inhaled colistin one month on, one month off. My CF doctor said it is safe to take during pregnancy because "the molecules are too large to pass from the lungs to the blood stream."

However, I have since read a journal article that took blood samples from patients after they inhaled colistin, and some did make it to their bloodstream. The amount was much lower than if they had taken it "systemically" (which I assume means via IV?). But still, now I am concerned.

Has anyone else talked to her doctor about taking colistin during pregnancy? If so, what did the doctor say?
 
K

Kristen

New member
I am currently on inhaled colistin one month on, one month off. My CF doctor said it is safe to take during pregnancy because "the molecules are too large to pass from the lungs to the blood stream."

However, I have since read a journal article that took blood samples from patients after they inhaled colistin, and some did make it to their bloodstream. The amount was much lower than if they had taken it "systemically" (which I assume means via IV?). But still, now I am concerned.

Has anyone else talked to her doctor about taking colistin during pregnancy? If so, what did the doctor say?
 
K

Kristen

New member
I am currently on inhaled colistin one month on, one month off. My CF doctor said it is safe to take during pregnancy because "the molecules are too large to pass from the lungs to the blood stream."
<br />
<br />However, I have since read a journal article that took blood samples from patients after they inhaled colistin, and some did make it to their bloodstream. The amount was much lower than if they had taken it "systemically" (which I assume means via IV?). But still, now I am concerned.
<br />
<br />Has anyone else talked to her doctor about taking colistin during pregnancy? If so, what did the doctor say?
 
R

rubyroselee

New member
Hi Kristen,

I used Colistin in my 4th month of pregnancy for a flare up. I currently do 3 weeks on/1 week off of Tobramycin and then use Colistin when I need something different. I am probably going to start doing Tobra/Colistin on an alternating basis though once I give birth.

Colistin is a category B drug, so it's considered safe for pregnancy. And of course, any antibiotic is safer to inhale than to go directly into the bloodstream. I believe very little of the drug gets into the blood when inhaled. That is why I was able to stay on the Tobramycin throughout my pregnancy. Normally it is a category D drug in pregnancy (which is toxic to the baby), but inhaled it is category B.

If you have an OB or RE, ask them about the safety of the drugs you're on if you're concerned. My CF doctor was also very good about the drugs to take and not take during pregnancy.

Good luck!
 
R

rubyroselee

New member
Hi Kristen,

I used Colistin in my 4th month of pregnancy for a flare up. I currently do 3 weeks on/1 week off of Tobramycin and then use Colistin when I need something different. I am probably going to start doing Tobra/Colistin on an alternating basis though once I give birth.

Colistin is a category B drug, so it's considered safe for pregnancy. And of course, any antibiotic is safer to inhale than to go directly into the bloodstream. I believe very little of the drug gets into the blood when inhaled. That is why I was able to stay on the Tobramycin throughout my pregnancy. Normally it is a category D drug in pregnancy (which is toxic to the baby), but inhaled it is category B.

If you have an OB or RE, ask them about the safety of the drugs you're on if you're concerned. My CF doctor was also very good about the drugs to take and not take during pregnancy.

Good luck!
 
R

rubyroselee

New member
Hi Kristen,

I used Colistin in my 4th month of pregnancy for a flare up. I currently do 3 weeks on/1 week off of Tobramycin and then use Colistin when I need something different. I am probably going to start doing Tobra/Colistin on an alternating basis though once I give birth.

Colistin is a category B drug, so it's considered safe for pregnancy. And of course, any antibiotic is safer to inhale than to go directly into the bloodstream. I believe very little of the drug gets into the blood when inhaled. That is why I was able to stay on the Tobramycin throughout my pregnancy. Normally it is a category D drug in pregnancy (which is toxic to the baby), but inhaled it is category B.

If you have an OB or RE, ask them about the safety of the drugs you're on if you're concerned. My CF doctor was also very good about the drugs to take and not take during pregnancy.

Good luck!
 
R

rubyroselee

New member
Hi Kristen,

I used Colistin in my 4th month of pregnancy for a flare up. I currently do 3 weeks on/1 week off of Tobramycin and then use Colistin when I need something different. I am probably going to start doing Tobra/Colistin on an alternating basis though once I give birth.

Colistin is a category B drug, so it's considered safe for pregnancy. And of course, any antibiotic is safer to inhale than to go directly into the bloodstream. I believe very little of the drug gets into the blood when inhaled. That is why I was able to stay on the Tobramycin throughout my pregnancy. Normally it is a category D drug in pregnancy (which is toxic to the baby), but inhaled it is category B.

If you have an OB or RE, ask them about the safety of the drugs you're on if you're concerned. My CF doctor was also very good about the drugs to take and not take during pregnancy.

Good luck!
 
R

rubyroselee

New member
Hi Kristen,
<br />
<br />I used Colistin in my 4th month of pregnancy for a flare up. I currently do 3 weeks on/1 week off of Tobramycin and then use Colistin when I need something different. I am probably going to start doing Tobra/Colistin on an alternating basis though once I give birth.
<br />
<br />Colistin is a category B drug, so it's considered safe for pregnancy. And of course, any antibiotic is safer to inhale than to go directly into the bloodstream. I believe very little of the drug gets into the blood when inhaled. That is why I was able to stay on the Tobramycin throughout my pregnancy. Normally it is a category D drug in pregnancy (which is toxic to the baby), but inhaled it is category B.
<br />
<br />If you have an OB or RE, ask them about the safety of the drugs you're on if you're concerned. My CF doctor was also very good about the drugs to take and not take during pregnancy.
<br />
<br />Good luck!
 
K

Kristen

New member
Really?! I didn't know that Colistin was only a category B, nor did I know that the category depended on the method the med is taken (all I saw was that it is a category C drug, but that must be because for when it is not inhaled). That's good to know. Thanks for easing my mind!

I did talk to my OB about it, but she didn't know much and took my CF doctor's word for it. It seems like most non-CF doctors I've seen haven't heard of inhaled Colistin.
 
K

Kristen

New member
Really?! I didn't know that Colistin was only a category B, nor did I know that the category depended on the method the med is taken (all I saw was that it is a category C drug, but that must be because for when it is not inhaled). That's good to know. Thanks for easing my mind!

I did talk to my OB about it, but she didn't know much and took my CF doctor's word for it. It seems like most non-CF doctors I've seen haven't heard of inhaled Colistin.
 
K

Kristen

New member
Really?! I didn't know that Colistin was only a category B, nor did I know that the category depended on the method the med is taken (all I saw was that it is a category C drug, but that must be because for when it is not inhaled). That's good to know. Thanks for easing my mind!

I did talk to my OB about it, but she didn't know much and took my CF doctor's word for it. It seems like most non-CF doctors I've seen haven't heard of inhaled Colistin.
 
K

Kristen

New member
Really?! I didn't know that Colistin was only a category B, nor did I know that the category depended on the method the med is taken (all I saw was that it is a category C drug, but that must be because for when it is not inhaled). That's good to know. Thanks for easing my mind!

I did talk to my OB about it, but she didn't know much and took my CF doctor's word for it. It seems like most non-CF doctors I've seen haven't heard of inhaled Colistin.
 
K

Kristen

New member
Really?! I didn't know that Colistin was only a category B, nor did I know that the category depended on the method the med is taken (all I saw was that it is a category C drug, but that must be because for when it is not inhaled). That's good to know. Thanks for easing my mind!
<br />
<br />I did talk to my OB about it, but she didn't know much and took my CF doctor's word for it. It seems like most non-CF doctors I've seen haven't heard of inhaled Colistin.
 
L

littlemisskris16

New member
At the chat that my dr had with my husband and I, he told us Coliston and Tobi are safe to inhale. I was curious bc Tobi does the trick for me, def keeps the pseudo at bay.

Can I ask a dumb question, what does DH stand for. I know I am going to slap my head after someone tells me... thanks ladies!

Kristy
31 NY'er with CF/rD
 
L

littlemisskris16

New member
At the chat that my dr had with my husband and I, he told us Coliston and Tobi are safe to inhale. I was curious bc Tobi does the trick for me, def keeps the pseudo at bay.

Can I ask a dumb question, what does DH stand for. I know I am going to slap my head after someone tells me... thanks ladies!

Kristy
31 NY'er with CF/rD
 
L

littlemisskris16

New member
At the chat that my dr had with my husband and I, he told us Coliston and Tobi are safe to inhale. I was curious bc Tobi does the trick for me, def keeps the pseudo at bay.

Can I ask a dumb question, what does DH stand for. I know I am going to slap my head after someone tells me... thanks ladies!

Kristy
31 NY'er with CF/rD
 
L

littlemisskris16

New member
At the chat that my dr had with my husband and I, he told us Coliston and Tobi are safe to inhale. I was curious bc Tobi does the trick for me, def keeps the pseudo at bay.

Can I ask a dumb question, what does DH stand for. I know I am going to slap my head after someone tells me... thanks ladies!

Kristy
31 NY'er with CF/rD
 
L

littlemisskris16

New member
At the chat that my dr had with my husband and I, he told us Coliston and Tobi are safe to inhale. I was curious bc Tobi does the trick for me, def keeps the pseudo at bay.
<br />
<br />Can I ask a dumb question, what does DH stand for. I know I am going to slap my head after someone tells me... thanks ladies!
<br />
<br />Kristy
<br />31 NY'er with CF/rD
 
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