I have been culturing staph aureus since the early 1980s. I wasn't diagnosed with CF until a year ago. I've been on and off oral antibiotics for a week or two here and there several times a year most of my life. It wasn't really a big deal. My recent decline in health 2 years ago was due to mycobacterium avium complex. The drugs to treat that made my staph mutate somewhat so the normal for me orals didn't work. Last fall I did 2 weeks of IV antibiotics to get my staph back under control. I've been off all abx since then and am back to my regular pre-cf dx health. Don't be afraid of staph aureus. I've never cultured pseudo or any other common CF bugs other than MAC. ~Juliet