Denufasol vs VX potentiator (VX-770?)

Jeana

New member
Okay, it appears to me by looking at other studies that 20 mL is about 1%. So, it appears that those on Denufosol had an FEV1 increase of about 6% after 48 weeks. The only thing that worries me is that if I get the placebo, since you aren't allowed to be on hypertonic that my lung function may decrease in the first year without hypertonic or Denufosol. The second year I would get to be on Denufosol for sure though...
 

Jeana

New member
Okay, it appears to me by looking at other studies that 20 mL is about 1%. So, it appears that those on Denufosol had an FEV1 increase of about 6% after 48 weeks. The only thing that worries me is that if I get the placebo, since you aren't allowed to be on hypertonic that my lung function may decrease in the first year without hypertonic or Denufosol. The second year I would get to be on Denufosol for sure though...
 

Jeana

New member
Okay, it appears to me by looking at other studies that 20 mL is about 1%. So, it appears that those on Denufosol had an FEV1 increase of about 6% after 48 weeks. The only thing that worries me is that if I get the placebo, since you aren't allowed to be on hypertonic that my lung function may decrease in the first year without hypertonic or Denufosol. The second year I would get to be on Denufosol for sure though...
 

Jeana

New member
Okay, it appears to me by looking at other studies that 20 mL is about 1%. So, it appears that those on Denufosol had an FEV1 increase of about 6% after 48 weeks. The only thing that worries me is that if I get the placebo, since you aren't allowed to be on hypertonic that my lung function may decrease in the first year without hypertonic or Denufosol. The second year I would get to be on Denufosol for sure though...
 

Jeana

New member
Okay, it appears to me by looking at other studies that 20 mL is about 1%. So, it appears that those on Denufosol had an FEV1 increase of about 6% after 48 weeks. The only thing that worries me is that if I get the placebo, since you aren't allowed to be on hypertonic that my lung function may decrease in the first year without hypertonic or Denufosol. The second year I would get to be on Denufosol for sure though...
 

dasjsmum

New member
Is that the phase three trial for vertex potentiator? I'm interested in finding out more about that if they're recruiting...are they recruiting for it now? I've been looking on the website to see if the phase three has started.

Thanks
 

dasjsmum

New member
Is that the phase three trial for vertex potentiator? I'm interested in finding out more about that if they're recruiting...are they recruiting for it now? I've been looking on the website to see if the phase three has started.

Thanks
 

dasjsmum

New member
Is that the phase three trial for vertex potentiator? I'm interested in finding out more about that if they're recruiting...are they recruiting for it now? I've been looking on the website to see if the phase three has started.

Thanks
 

dasjsmum

New member
Is that the phase three trial for vertex potentiator? I'm interested in finding out more about that if they're recruiting...are they recruiting for it now? I've been looking on the website to see if the phase three has started.

Thanks
 

dasjsmum

New member
Is that the phase three trial for vertex potentiator? I'm interested in finding out more about that if they're recruiting...are they recruiting for it now? I've been looking on the website to see if the phase three has started.
<br />
<br />Thanks
 
S

semperfiohana

Guest
vx is only in phase 2, here's a link for that trial.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a>
 
S

semperfiohana

Guest
vx is only in phase 2, here's a link for that trial.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a>
 
S

semperfiohana

Guest
vx is only in phase 2, here's a link for that trial.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a>
 
S

semperfiohana

Guest
vx is only in phase 2, here's a link for that trial.

<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a>
 
S

semperfiohana

Guest
vx is only in phase 2, here's a link for that trial.
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a>
 

saveferris2009

New member
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>semperfiohana</b></i>

vx is only in phase 2, here's a link for that trial.



<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a></end quote></div>



There are actuallly two VX meds: VX809 (entering Phase II) and VX770 (entering Phase III). So I'm not sure which you will be doing Jeanna.

Lots more info on my blog
 

saveferris2009

New member
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>semperfiohana</b></i>

vx is only in phase 2, here's a link for that trial.



<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a></end quote></div>



There are actuallly two VX meds: VX809 (entering Phase II) and VX770 (entering Phase III). So I'm not sure which you will be doing Jeanna.

Lots more info on my blog
 

saveferris2009

New member
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>semperfiohana</b></i>

vx is only in phase 2, here's a link for that trial.



<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a></end quote></div>



There are actuallly two VX meds: VX809 (entering Phase II) and VX770 (entering Phase III). So I'm not sure which you will be doing Jeanna.

Lots more info on my blog
 

saveferris2009

New member
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>semperfiohana</b></i>

vx is only in phase 2, here's a link for that trial.



<a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a></end quote>



There are actuallly two VX meds: VX809 (entering Phase II) and VX770 (entering Phase III). So I'm not sure which you will be doing Jeanna.

Lots more info on my blog
 

saveferris2009

New member
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>semperfiohana</b></i>
<br />
<br />vx is only in phase 2, here's a link for that trial.
<br />
<br />
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://www.clinicaltrials.gov/ct2/show/NCT00865904?term=vx-809&rank=1&show_locs=Y#locn">http://www.clinicaltrials.gov/...ank=1&show_locs=Y#locn</a></end quote>
<br />
<br />
<br />
<br />There are actuallly two VX meds: VX809 (entering Phase II) and VX770 (entering Phase III). So I'm not sure which you will be doing Jeanna.
<br />
<br />Lots more info on my blog
 
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