I just wanted to say I would call your CF nurse/center too. Let them know your baby has their first cold and get their input. As your child gets older, I think it's a little easier to tell if the cough/cold warrants antibiotics but when they are little, can't talk and you, yourself are learning how to take care of a Cf child, it's a little harder. My daughter is 4 and when she gets a cold/cough, we up her VEST(airway clearance) time, do extra nebs(albuteral) get her in a steamy bath to let the mucus run, do Saline nasal spray up the nose. If Maggie does not have a fever or her cough is not upper airway or chesty sounding, I 'll just keep up with aggressive airway clearance for a while before calling Cf clinic. I can tell she needs antibiotics, when she's looking tired, dark rings around her eyes, coughing that keeps her up at night, her appetite decreases. You WIll get to know how your child responds to colds. Babies airways are so small, so I think it's a very good idea to call the Cf clinic. They may want to do a culture just to make sure the baby isn't culturing anything. i still worry with every virus, cough and cold. But I have seen my daughter get through colds without needing antibiotics, especially before she regularly started culturing staph.