What is she on? When it comes to the stimulant laxatives, you can run into problems with dependance w/long term use and even damage to the intestine if too much is used over time. Various tool softeners (i.e. Miralax, etc) are often used long-term for our kids as they draw water to the colon to make the stool easier to pass, and can have a beneficial effect with cf kids in helping thin the thick mucus that can build up in their GI tract. Anything to help in this area needs to be taken with a LOT of clear fluids to get the most benefit.
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<br />Re. the enzymes~ taken when there is a need for them, they should not cause constipation. When taken in excess they can, but there are guidelines for dosage that the dr and dietician use.
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<br />Malabsorbing itself can cause such bulky stools that going can be difficult, and muscle tone to the colon and rectum can be affected by long-time unusually bulky stool (this happened with Emily and eventually resulted in problems with rectal prolapse.) At any rate, without good muscle control in that area, coordinating everything to 'go' when needed can be affected, or having a long hx of bulky stools can result in hemorrhoids or fissures which can also make going painful (also an issue for Emily at times, even when stool is not overly hard and resulted in her holding it at times until she was desperate to go.)
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<br />I know this got long... just wanted to let you know Emily has had assorted gi issues as well, and if anything could help i wanted to share it.