Elevated liver enzymes/Vertex meds


New member
Hello Friends!
I have a few questions for those of you who have taken the Vertex modulators and experienced elevated liver enzymes. How elevated did your numbers become? Did your doctor take you off the medications right away? Did you ever go back after a break? Did liver enzymes ever resolve if so? I would appreciate any information from those of you who can shed some light on this.
Thanks so much,


New member
I typed this long reply but I don't think it went through. I still have elevated enzyme levels and unfortunately liver damage. May be from cf in general. I take ursodial (actigal) 3x daily for treatment. I see a GI that specializes in cf liver disease in Denver at National Jewish.