I take 3 Pancrease MT20s with meals, and weigh about 72-73 pounds.Julie-- you are partially correct, but weight does play a factor in enzyme dosages. When a person is very pancreatic insufficient, there is a maximum dosage of enzymes allowed based on the weight of the patient. I think the sanction was put into place because of colonic strictures due to overdosage of enzymes. I only know this because when I was younger, my enzyme dosage was reduced when the sanction was put into place.