Hey,
Well we can only do so much to avoid inhaling smoke. You said that it is an amazing opportunity so if its only once a week, or a few nights or whatever I think you should go ahead and do it. If it was every night I don't think that would be the best idea. In saying that, if you feel your health can handle a bit of extra exposure to smoke and that the opportunity could do a lot for your comedy career, then I say you should go ahead!