I have used HTS for about a year now and I wouldnt be here without it .I am out of options as far as antibiodics are concerned I have 2 different strands of cepacia that is resistant to everything. So the HTS is a lifesaver .It really helps me bring out the mucus it is harsh at first until you get used to it. Make sure and drink a lot of water that seems to help me with thinning the mucus. The salt draws water and if it isn't there It wont work as well.That's my experience with HTS . I have noticed that if I drink a coke or 2 a day instead of more water my cough is not as productive and have more wheezing . And I do use aluterol before using HTS