Here is an email from the pharmacologist on my cf team:
<div class="FTQUOTE"><begin quote><u>High dose</u> ibuprofen (~ 1000 mg twice daily) <u>reduces</u> inflammation and improves lung function in CF patients with mild lung disease;
however,
experimental data showed that <u>lower doses</u> may actually <u>increase</u> inflammation.
Therefore, it is possible that you could feel worse on ibuprofen therapy.
<b><i>We do not use much chronic ibuprofen therapy because of concerns for hemoptysis and risk of kidney failure.</i></b><div class="FTQUOTE"><begin quote>