I recently wrote a blog post about the latest Vertex news (includes info from the Dec and Jan press releases & investor conferences). Since I wrote this post it has also been announced that the combination therapy VX661/Ivacaftor has been granted breakthrough FDA designation.
http://sixtyfiverosesblog.wordpress.com/2014/01/29/january-vertex-update/
http://sixtyfiverosesblog.wordpress.com/2014/01/29/january-vertex-update/