I did not have any problems, when I inhaled the Tobramycin for injection once, but I did get problems with the Tobi!
So in my opinion the approvement is not everything...especially if you think who has to test a special medicine for cf: only a test by Cfers will be of any use, but as we are already sick, noone knows what reactions will come due to the different forms of cf and you will not know the long-term-effects for shure because either the test-person will die relatively early or you won´t know, if any problems are caused by the medication or cf itself...
Uli,43,Germany