link for additional info on more mutations that may benefit from Ivacaftor

musclemania70

New member
(this info may not be new to you but worthy for some who haven't seen it)
Starting at slide 21

<a href="https://docs.google.com/viewer?a=v&q=cache:6uiGqI8lbLoJ:iom.edu/~/media/Files/Activity%2520Files/Research/GenomicBasedResearch/2012-MAR-21/3%2520-%2520Peter%2520Mueller.pdf+vertex+a+genetic+approach+to+the+treatment+of&hl=en&gl=us&pid=bl&srcid=ADGEESgQlYUup4CFBrMHh_amIY3xA7fwP_ZOkNgp8HuogmXKPRAAnC2wwbjbrb6qVSgLR9Oc17egibnUFRIcqHKGUkFN4hSLcOStBdTzM0LhaoOD7eVUN94zD6WqY3iRp9gWcbP5e-I4&sig=AHIEtbS0XWqKaeAfmfTTxGBdh0CQmmiYNQ">https://docs.google.com/viewer?a=v&q=cache:6uiGqI8lbLoJ:iom.edu/~/media/Files/Activity%2520Files/Research/GenomicBasedResearch/2012-MAR-21/3%2520-%2520Peter%2520Mueller.pdf+vertex+a+genetic+approach+to+the+treatment+of&hl=en&gl=us&pid=bl&srcid=ADGEESgQlYUup4CFBrMHh_amIY3xA7fwP_ZOkNgp8HuogmXKPRAAnC2wwbjbrb6qVSgLR9Oc17egibnUFRIcqHKGUkFN4hSLcOStBdTzM0LhaoOD7eVUN94zD6WqY3iRp9gWcbP5e-I4&sig=AHIEtbS0XWqKaeAfmfTTxGBdh0CQmmiYNQ</a>
 

musclemania70

New member
(this info may not be new to you but worthy for some who haven't seen it)
Starting at slide 21

<a href="https://docs.google.com/viewer?a=v&q=cache:6uiGqI8lbLoJ:iom.edu/~/media/Files/Activity%2520Files/Research/GenomicBasedResearch/2012-MAR-21/3%2520-%2520Peter%2520Mueller.pdf+vertex+a+genetic+approach+to+the+treatment+of&hl=en&gl=us&pid=bl&srcid=ADGEESgQlYUup4CFBrMHh_amIY3xA7fwP_ZOkNgp8HuogmXKPRAAnC2wwbjbrb6qVSgLR9Oc17egibnUFRIcqHKGUkFN4hSLcOStBdTzM0LhaoOD7eVUN94zD6WqY3iRp9gWcbP5e-I4&sig=AHIEtbS0XWqKaeAfmfTTxGBdh0CQmmiYNQ">https://docs.google.com/viewer?a=v&q=cache:6uiGqI8lbLoJ:iom.edu/~/media/Files/Activity%2520Files/Research/GenomicBasedResearch/2012-MAR-21/3%2520-%2520Peter%2520Mueller.pdf+vertex+a+genetic+approach+to+the+treatment+of&hl=en&gl=us&pid=bl&srcid=ADGEESgQlYUup4CFBrMHh_amIY3xA7fwP_ZOkNgp8HuogmXKPRAAnC2wwbjbrb6qVSgLR9Oc17egibnUFRIcqHKGUkFN4hSLcOStBdTzM0LhaoOD7eVUN94zD6WqY3iRp9gWcbP5e-I4&sig=AHIEtbS0XWqKaeAfmfTTxGBdh0CQmmiYNQ</a>
 

dramamama

New member
This shows what I have been anticipating <img src="i/expressions/face-icon-small-smile.gif" border="0"> We are going to be our own individual studies... study in a box!!! brilliant!!! Thank you Vertex.
 

dramamama

New member
This shows what I have been anticipating <img src="i/expressions/face-icon-small-smile.gif" border="0"> We are going to be our own individual studies... study in a box!!! brilliant!!! Thank you Vertex.
 
S

stranger

Guest
The quote from the FDA was: 'personalized' medicine. Maybe they got that from this slide deck?

I am somewhat surprised that data from 809 was included in something publicly available just prior to VRTX announcing their quarterly earnings (I believe the 26th?).
 
S

stranger

Guest
The quote from the FDA was: 'personalized' medicine. Maybe they got that from this slide deck?

I am somewhat surprised that data from 809 was included in something publicly available just prior to VRTX announcing their quarterly earnings (I believe the 26th?).
 

musclemania70

New member
dramamama, did you post the link to the FB page? That's great! I don't have FB and want to get this info out there!! Super important to get this data shared and get it out in the open where people will read it and USE IT!!!

Save the pdf if you can to your computer. I have a feeling this link is not going to work for very long......
 

musclemania70

New member
dramamama, did you post the link to the FB page? That's great! I don't have FB and want to get this info out there!! Super important to get this data shared and get it out in the open where people will read it and USE IT!!!

Save the pdf if you can to your computer. I have a feeling this link is not going to work for very long......
 

ymikhale

New member
I looked through this presentation but am confused somewhat: are they saying Kalydeco might work for splicing mutations as well?
 

ymikhale

New member
I looked through this presentation but am confused somewhat: are they saying Kalydeco might work for splicing mutations as well?
 
S

SarahProcter

Guest
Am I correctly interpreting this to say that pancreatic sufficiency indicates that Kalydeco may be of use, and hence that a pancreatic sufficient person with CF would be a reasonable candidate for the drug?
 
S

SarahProcter

Guest
Am I correctly interpreting this to say that pancreatic sufficiency indicates that Kalydeco may be of use, and hence that a pancreatic sufficient person with CF would be a reasonable candidate for the drug?
 
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