Looking for chart showing bacteria/average age of detection.

[Aboveallislove]

At one of our first CF appointments our CF Doctor showed us a table that listed the typical bacteria detected in CFers in cultures and the average age (and %?) of infection. Does anyone have a link to this chart?

 

[Melissa75]

I googled "cf bacteria age of colonization"

There is a chart here:

http://mic.sgmjournals.org/content/153/4/917.full

And an interesting article with other charts.

http://www.the-aps.org/mm/Publications/Journals/PIM/starner-pdf.pdf

 

[TonyaH]

Thanks for sharing, Melissa...
It would be interesting to see statistics for Mycobacterium Abcessus and Aspergillus.

 

[Melissa75]

You're welcome, Tonya. (Nice work shuffling threads, btw.) This article doesn't discuss age, but it says Aspergillus is a risk factor for development of M. Abscessus. "In conclusion, severe nontuberculous mycobacterial lung disease, particularly with Mycobacterium abscessus, is becoming a perplexing challenge in cystic fibrosis patients. Allergic bronchopulmonary aspergillosis and systemic steroids appear to be risk factors..." http://erj.ersjournals.com/content/25/2/324.full Page 4, 15% of CF patients have an NTM (again no age). http://www.hopkinscme.net/ofp/eCysticFibrosisReview/newsletters/2012/0612.pdf And the unpleasant "between a rock and a hard place" research about zithro contributing to the rise in M. Abscessus. http://www.jci.org/articles/view/46095 On a side note, my last CT scan had nodules all over the place, some "masslike." The pulmo (a CF dr) said both Aspergillus and NTMs look like this on scans. (We're doing no treatment at this point since I am feeling good and culture neg for both, but we'll do more cultures and repeat scan some time in the future.) Edited to add, I included this info because I wonder if the two are complimentary in their attack, rather than just the steroids and zithro allowing for NTMs to gain a foothold.

 

[jbrandyn]

My doc said aspergillus just kind of happens when it happens. Usually it has an environmental cause, for instance I got it after being being around mold and it gets worse during wet and humid seasons. I don't know if that is typical, but it seems like it would be.

They may be, I was tested for both at the same time when I got lung masses. Turns out I am just really allergic to aspergillus, and my apartment had mold wso the masses were inflamed tissue... not fun times.

 

[Mistyjo]

I found this article about residual cftr function vs minimal cftr function and when to expect to culture cf bacteria. In the article are tables with average age of when to expect to culture. Jasey is residual cftr function, I think.
Www.biomedcentral.com/content/pdf/1465-99-21-11-140.pdf

 

[Aboveallislove]

Thanks so much Melissa--sorry for delay in responding we're doing "cyber-free weekends" now, so I catch up later in the week. Greatly appreciate all the info!!

 

[Melissa75]

Jbrandyn, Thanks for sharing. I do get lower-left-achy lobe when the air is damp.
Aboveallislove, You're welcome.