I am four months pregnant and i have the gene for CF. i just found out about it about 2 hrs ago. they want to screen my husband for the gene as well but he is over seas in the Navy. How else may i go about finding if he has the gene. His sister just had a baby. If she is clear of the CF gene then will my husband be like his sister and be Clear of the CF gene?<b>Text</b>
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My Unborn Baby And CF
- Thread starter anonymous
- Start date
It gets a bit complicated so I suggest you read for yourself & apply the necessary information from your family accordingly. Please check out this site:
<a target=new class=ftalternatingbarlinklarge href="http://www.phd.msu.edu/DNA/cf_family3.html
">http://www.phd.msu.edu/DNA/cf_family3.html
</a>
Good Luck & if you still have questions.....please ask
<a target=new class=ftalternatingbarlinklarge href="http://www.phd.msu.edu/DNA/cf_family3.html
">http://www.phd.msu.edu/DNA/cf_family3.html
</a>
Good Luck & if you still have questions.....please ask
I
IG
Guest
I'm sure there would be a way to tell, but since I'm not mathematically inclined I have no clue as to what it is.
Genetics works like this though.
If a parent carries the gene, and the other parent doesn't then there is a 50/50 chance that <b>each</b> child will carry the gene. So your husband might not carry the gene and his sister might because they each had those odds.
So honestly, unless he himself is tested, there's not a correlation [that I'm willing to come up with] that will tell what you want to know. That or see about an amniocentesis [which I don't know if that's an option yet, due to only being 4 months pregnant] Anyway I know this probably isn't the information you want, but I hope it clears things up.
Genetics works like this though.
If a parent carries the gene, and the other parent doesn't then there is a 50/50 chance that <b>each</b> child will carry the gene. So your husband might not carry the gene and his sister might because they each had those odds.
So honestly, unless he himself is tested, there's not a correlation [that I'm willing to come up with] that will tell what you want to know. That or see about an amniocentesis [which I don't know if that's an option yet, due to only being 4 months pregnant] Anyway I know this probably isn't the information you want, but I hope it clears things up.
the sad thing is that i have taken mutliple genetics courses but my mind is all clouded right now. thanks for putting it simple for me. i am just stressing because i can't get ahold of my husband and the baby can feel the stress and it hurts sooo much. so i am just not thinking clearly.
There is no way to determine your husbands carrier status from his sibling. Where overseas is he? The can still do a blood draw on him, either on a ship or in iraq. are you in communication with him? If not, I recommend that you contact his chain of command that is state side and ask for their assistance to get in contact with him. I am active duty navy as well...
thanks for your replies but i already got ahold of my husband a few hours after i started the forum topic. he's trying to get blood drawn but he has to go through his chain and right now doc is at the hospital cus some one fell down the stairs. we just have to wait our turn. i know ur thinking why doesnt my husband go to the hospital on his own... my husband in on duty today.
N
nycgirl
Guest
hi,
well, it is a bit complicated. i am sure you must have so many questions and want answers now.
this is my scenerio. i have cystic fibrosis. my siblings, my brother and sister do not even carry the gene. strange right?
is there any way you can ship off a swab sample to him in the navy? ( i think you said navy )
my ex fiance lived in italy, and i am in NYC. we ( my genetic counselor and I ) shipped of a swab sample so he could swab the inside of his mouth and then he sent it to a lab in california to see if he was a carrier.
that might be an option to explore.
good luck
well, it is a bit complicated. i am sure you must have so many questions and want answers now.
this is my scenerio. i have cystic fibrosis. my siblings, my brother and sister do not even carry the gene. strange right?
is there any way you can ship off a swab sample to him in the navy? ( i think you said navy )
my ex fiance lived in italy, and i am in NYC. we ( my genetic counselor and I ) shipped of a swab sample so he could swab the inside of his mouth and then he sent it to a lab in california to see if he was a carrier.
that might be an option to explore.
good luck
hi it's me again... orginator of the topic.
it's all being taken care of. it's still just a wait and see game that i think has me all up in knots.
If both parents carry the gene, there is a 25% chance of having a child with no genetic problem. However, there is a 25% chance of having a child with CF and a 50% chance of having a child who is a carrier. This means the child does not have CF but can pass the disease or trait to his or her children.
If only one parent is a carrier of a defective CFTR gene, the child will not have CF, and there is a 50% chance that the child will have no genetic problem. However, there is a 50% chance that the child will be a CF carrier.
it's all being taken care of. it's still just a wait and see game that i think has me all up in knots.
If both parents carry the gene, there is a 25% chance of having a child with no genetic problem. However, there is a 25% chance of having a child with CF and a 50% chance of having a child who is a carrier. This means the child does not have CF but can pass the disease or trait to his or her children.
If only one parent is a carrier of a defective CFTR gene, the child will not have CF, and there is a 50% chance that the child will have no genetic problem. However, there is a 50% chance that the child will be a CF carrier.
thefrogprincess
New member
You could always have an amnio. But all that would tell you is whether or not the baby has CF. If the baby does have then your husband is a carrier. If the baby does not then your husband may still be a carrier and you would want to have him screened before having any more kids. Good luck!
You meant 75% chance of having a healthy baby right? If you are both carriers, the baby has a 25% chance of having CF. We found out with this pregnancy that my husband and I are both carriers and decided not to do the amnio because of the risks. We are going to have our baby's cord blood tested when she is born. I freaked at first, but after getting on this site daily and learning more about CF, I really don't think about it. I am just trying to enjoy this pregnancy since it will probably be our last and we will deal with whatever comes our way - we always do! Good luck to you.
I
IG
Guest
25% chance of CF, 50% chance of carrying the gene, and a 25% chance of being free of CF or the gene.
The phenotype [how it physically looks] your child would have a 75% chance of no CF whatsoever and be 'healthy' although still carry the gene but since that doesn't apparently manifest itself physically it wouldn't show up as a phenotype and still be 75% for non CF. If that makes any sense whatsoever.
The phenotype [how it physically looks] your child would have a 75% chance of no CF whatsoever and be 'healthy' although still carry the gene but since that doesn't apparently manifest itself physically it wouldn't show up as a phenotype and still be 75% for non CF. If that makes any sense whatsoever.
Hi, my name is Jennifer. I am a 24 year old with CF and am trying to conceive. I have been through the genetic testing hoops that you are now facing. Since I have CF, both of my genes are positive. My husband got the genetic testing and both of his genes are negative. Therefore, our baby has less than a 10% chance of having CF. However, our baby would have a 25% chance of being a carrier with no symptoms.
My recommedation for you is:
1. Since your husband is not able to get tested, I would recommend getting both of his parents tested for the gene. That would probably be the next best thing. Hopefully, you know both of his parents. If you don't or only one consents to the testing, the test will mean nothing. ONLY ONE PARENT HAS TO CARRY THE GENE FOR HIM TO BE A CARRIER. TWO PARENTS MUST CARRY THE GENE TO HAVE A CHILD WITH CF. A CARRIER OF THE GENE USUALLY DOES NOT KNOW UNTIL IT IS TOO LATE! THAT IS HOW I WAS BORN WITH CF. MY FAMILY HAD NO HISTORY OF THE DISEASE.
2. If you can't do the testing on both of his parents, you could have his siblings tested. However, if for example his sister is negative to carry the gene, that doesn't mean he doesn't care the gene. IF MY HUSBAND AND I HAVE TWO CHILDREN, EACH ONE HAS A 25% CHANCE OF CARRYING THE GENE. ONE MIGHT - ONE MIGHT NOT.
THE BEST CHANCE WOULD BE TO GET HIS PARENTS TESTED.
But please don't get upset. Only 1 out of 32 white Americans carry the gene. Only 1 out of 62 Hispanic carry the gene. And only 1 out of 78 Blacks carry the gene. I think it is unlikely your baby will have CF. He or she may be a carrier. But I highly doubt your baby will have CF. I will always offer you and your husband support.
Jenny
My recommedation for you is:
1. Since your husband is not able to get tested, I would recommend getting both of his parents tested for the gene. That would probably be the next best thing. Hopefully, you know both of his parents. If you don't or only one consents to the testing, the test will mean nothing. ONLY ONE PARENT HAS TO CARRY THE GENE FOR HIM TO BE A CARRIER. TWO PARENTS MUST CARRY THE GENE TO HAVE A CHILD WITH CF. A CARRIER OF THE GENE USUALLY DOES NOT KNOW UNTIL IT IS TOO LATE! THAT IS HOW I WAS BORN WITH CF. MY FAMILY HAD NO HISTORY OF THE DISEASE.
2. If you can't do the testing on both of his parents, you could have his siblings tested. However, if for example his sister is negative to carry the gene, that doesn't mean he doesn't care the gene. IF MY HUSBAND AND I HAVE TWO CHILDREN, EACH ONE HAS A 25% CHANCE OF CARRYING THE GENE. ONE MIGHT - ONE MIGHT NOT.
THE BEST CHANCE WOULD BE TO GET HIS PARENTS TESTED.
But please don't get upset. Only 1 out of 32 white Americans carry the gene. Only 1 out of 62 Hispanic carry the gene. And only 1 out of 78 Blacks carry the gene. I think it is unlikely your baby will have CF. He or she may be a carrier. But I highly doubt your baby will have CF. I will always offer you and your husband support.
Jenny
Hi, my name is Jennifer. I am a 24 year old with CF and am trying to conceive. I have been through the genetic testing hoops that you are now facing. Since I have CF, both of my genes are positive. My husband got the genetic testing and both of his genes are negative. Therefore, our baby has less than a 10% chance of having CF. However, our baby would have a 25% chance of being a carrier with no symptoms.
My recommedation for you is:
1. Since your husband is not able to get tested, I would recommend getting both of his parents tested for the gene. That would probably be the next best thing. Hopefully, you know both of his parents. If you don't or only one consents to the testing, the test will mean nothing. ONLY ONE PARENT HAS TO CARRY THE GENE FOR HIM TO BE A CARRIER. TWO PARENTS MUST CARRY THE GENE TO HAVE A CHILD WITH CF. A CARRIER OF THE GENE USUALLY DOES NOT KNOW UNTIL IT IS TOO LATE! THAT IS HOW I WAS BORN WITH CF. MY FAMILY HAD NO HISTORY OF THE DISEASE.
2. If you can't do the testing on both of his parents, you could have his siblings tested. However, if for example his sister is negative to carry the gene, that doesn't mean he doesn't care the gene. IF MY HUSBAND AND I HAVE TWO CHILDREN, EACH ONE HAS A 25% CHANCE OF CARRYING THE GENE. ONE MIGHT - ONE MIGHT NOT.
THE BEST CHANCE WOULD BE TO GET HIS PARENTS TESTED.
But please don't get upset. Only 1 out of 32 white Americans carry the gene. Only 1 out of 62 Hispanic carry the gene. And only 1 out of 78 Blacks carry the gene. I think it is unlikely your baby will have CF. He or she may be a carrier. But I highly doubt your baby will have CF. I will always offer you and your husband support.
Jenny
My recommedation for you is:
1. Since your husband is not able to get tested, I would recommend getting both of his parents tested for the gene. That would probably be the next best thing. Hopefully, you know both of his parents. If you don't or only one consents to the testing, the test will mean nothing. ONLY ONE PARENT HAS TO CARRY THE GENE FOR HIM TO BE A CARRIER. TWO PARENTS MUST CARRY THE GENE TO HAVE A CHILD WITH CF. A CARRIER OF THE GENE USUALLY DOES NOT KNOW UNTIL IT IS TOO LATE! THAT IS HOW I WAS BORN WITH CF. MY FAMILY HAD NO HISTORY OF THE DISEASE.
2. If you can't do the testing on both of his parents, you could have his siblings tested. However, if for example his sister is negative to carry the gene, that doesn't mean he doesn't care the gene. IF MY HUSBAND AND I HAVE TWO CHILDREN, EACH ONE HAS A 25% CHANCE OF CARRYING THE GENE. ONE MIGHT - ONE MIGHT NOT.
THE BEST CHANCE WOULD BE TO GET HIS PARENTS TESTED.
But please don't get upset. Only 1 out of 32 white Americans carry the gene. Only 1 out of 62 Hispanic carry the gene. And only 1 out of 78 Blacks carry the gene. I think it is unlikely your baby will have CF. He or she may be a carrier. But I highly doubt your baby will have CF. I will always offer you and your husband support.
Jenny
Um, not to burst your bubble, Jenny, but if you and your husband have children, there is a 100% chance your children will carry the gene. Since you have both alelles for CF, and you husband had none, YOur punnet square would look something like this. YOu= cc , because Cf is recessive, your husband = CC. Your kids= Cc
c c
C Cc Cc
C Cc Cc
IT's explained much better here http://www.cysticfibrosismaleinfertility.com/Before_you_begin.html
c c
C Cc Cc
C Cc Cc
IT's explained much better here http://www.cysticfibrosismaleinfertility.com/Before_you_begin.html
Allie and Anonymous,
As far as having a child as a carrier of CF, I completely understanding what you are telling me. That is what I thought initially. My doctors were the ones to tell me that a child would only have a 25 % chance of having a child that carries CF. I believe what you are telling me. Especially with the punnet square as you mentioned Allie.
As far as having a child as a carrier of CF, I completely understanding what you are telling me. That is what I thought initially. My doctors were the ones to tell me that a child would only have a 25 % chance of having a child that carries CF. I believe what you are telling me. Especially with the punnet square as you mentioned Allie.