Not sure what to do

[janddburke]

my daughter had 3 sweat tests from 5 months to a year old. not one was positive. Confirmed diagnosis thru bloodwork.
her scores were higher, but still not definitive diagnosis range.
not sure why they still do sweat tests?

 

[janddburke]

my daughter had 3 sweat tests from 5 months to a year old. not one was positive. Confirmed diagnosis thru bloodwork.
her scores were higher, but still not definitive diagnosis range.
not sure why they still do sweat tests?

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.

 

[okok]

I just want to say that r117h is a mutation that is often associated with lower sweat chloride values (but usually greater than 30.) About 23% of people with sweat chloride greater than 30 have two CF mutations but 10 is still pretty low....

The sweat test is useful although it is subject to both false postive and false negative results. It is also important that it is preformed properly since incorrect procedure increases the rates of false negative and false positive results. The sweat test is especially handy when no mutations can be found (new mutations can occur at any time so there may be some unknown) or when genetic variation is detected that might not actually be disease causing. It is important that sweat test results are interpreted by a knoledgeable doctor. I don't think they are completely out of date or useless though.