OK science people

wanderlost

New member
Had a clinic appt. today (I'll write about it in my blog if you're interested). Was saying I thought I might need another does of antibiotics, but b/c of the breastfeeding, I was limited on what I can and cannot take. So I asked to see my lab sheet that shows my susceptibilites so I could look up the drugs in my handy handy <i>Medications and Mothers' Milk</i> <---my new bible. Anyway, going down the list the doc is like - thats' IV, IV IV...and IVs are not an option right now for me. Cipro is not the best choice for breastfeeding, which leaves Levaquin. Anyway, that ain't the point....the point is, we get to Tobi - and guess what? I am resistant to Tobi. Funny thing is, I have never taken Tobi a day in my life. So how on earth did I pick up a Tobi resistent strain of PA all the while still being susceptible to a range of other drugs?? I had to have gotten that at clinic, no? Someone explain this to me - and what does this mean? That once i have exhausted all the other drugs I am just SOL since I can't use Tobi? I need more info!!!!
 

wanderlost

New member
Had a clinic appt. today (I'll write about it in my blog if you're interested). Was saying I thought I might need another does of antibiotics, but b/c of the breastfeeding, I was limited on what I can and cannot take. So I asked to see my lab sheet that shows my susceptibilites so I could look up the drugs in my handy handy <i>Medications and Mothers' Milk</i> <---my new bible. Anyway, going down the list the doc is like - thats' IV, IV IV...and IVs are not an option right now for me. Cipro is not the best choice for breastfeeding, which leaves Levaquin. Anyway, that ain't the point....the point is, we get to Tobi - and guess what? I am resistant to Tobi. Funny thing is, I have never taken Tobi a day in my life. So how on earth did I pick up a Tobi resistent strain of PA all the while still being susceptible to a range of other drugs?? I had to have gotten that at clinic, no? Someone explain this to me - and what does this mean? That once i have exhausted all the other drugs I am just SOL since I can't use Tobi? I need more info!!!!
 

wanderlost

New member
Had a clinic appt. today (I'll write about it in my blog if you're interested). Was saying I thought I might need another does of antibiotics, but b/c of the breastfeeding, I was limited on what I can and cannot take. So I asked to see my lab sheet that shows my susceptibilites so I could look up the drugs in my handy handy <i>Medications and Mothers' Milk</i> <---my new bible. Anyway, going down the list the doc is like - thats' IV, IV IV...and IVs are not an option right now for me. Cipro is not the best choice for breastfeeding, which leaves Levaquin. Anyway, that ain't the point....the point is, we get to Tobi - and guess what? I am resistant to Tobi. Funny thing is, I have never taken Tobi a day in my life. So how on earth did I pick up a Tobi resistent strain of PA all the while still being susceptible to a range of other drugs?? I had to have gotten that at clinic, no? Someone explain this to me - and what does this mean? That once i have exhausted all the other drugs I am just SOL since I can't use Tobi? I need more info!!!!
 

Diane

New member
it is odd the way that stuff works isnt it? I always check out my list of recent sputum cultures when i am at the Doctors and i have resistances to things i have never been on also. I also am resistant to just about all antibiotics but yet they still work most of the time. They work especiallly well when they are paired up with another. They seem to work synergistically, and it is also harder for the bacteria to become resistant to either while you are on two ( or more) at a time. I'll never understand it all either, but it's good to know when you are resistant to antibiotics you really arent completely out of options.
 

Diane

New member
it is odd the way that stuff works isnt it? I always check out my list of recent sputum cultures when i am at the Doctors and i have resistances to things i have never been on also. I also am resistant to just about all antibiotics but yet they still work most of the time. They work especiallly well when they are paired up with another. They seem to work synergistically, and it is also harder for the bacteria to become resistant to either while you are on two ( or more) at a time. I'll never understand it all either, but it's good to know when you are resistant to antibiotics you really arent completely out of options.
 

Diane

New member
it is odd the way that stuff works isnt it? I always check out my list of recent sputum cultures when i am at the Doctors and i have resistances to things i have never been on also. I also am resistant to just about all antibiotics but yet they still work most of the time. They work especiallly well when they are paired up with another. They seem to work synergistically, and it is also harder for the bacteria to become resistant to either while you are on two ( or more) at a time. I'll never understand it all either, but it's good to know when you are resistant to antibiotics you really arent completely out of options.
 

Lilith

New member
Hmm, I really don't know. It is very possible that you picked it up at your clinic. For me personally, I became resistant to Tobi some time ago, but about a year later, it showed that I was able to take it again. I have no clue why, it just did. These things can be weird sometimes... But I don't think you're SOL. There are a lot of antibiotics you'd have to go through first. I wouldn't worry about it. You might be like me and the strain could die off. Who knows with these things.
 

Lilith

New member
Hmm, I really don't know. It is very possible that you picked it up at your clinic. For me personally, I became resistant to Tobi some time ago, but about a year later, it showed that I was able to take it again. I have no clue why, it just did. These things can be weird sometimes... But I don't think you're SOL. There are a lot of antibiotics you'd have to go through first. I wouldn't worry about it. You might be like me and the strain could die off. Who knows with these things.
 

Lilith

New member
Hmm, I really don't know. It is very possible that you picked it up at your clinic. For me personally, I became resistant to Tobi some time ago, but about a year later, it showed that I was able to take it again. I have no clue why, it just did. These things can be weird sometimes... But I don't think you're SOL. There are a lot of antibiotics you'd have to go through first. I wouldn't worry about it. You might be like me and the strain could die off. Who knows with these things.
 

Scarlett81

New member
Wow I'm really sorry you are in this lousy situation right now.
Just wanted to say that-I have no clue about the rest. I guess it would seem logical that you picked it up in the clinic or hosp. Where else would you get it?!

Are they sure you are resistant to tobi? Have you tried Tobi yet? You know they thought once I was resistant to Augmentin and then my new doc tried it, b/c she had a theory that it wasn't true, and she was right. This was years back so I can't explain the facts in scientific terms to you, sorry. Just a thought. They aren't always right.

wow, I wish I could say something to help you! I'd be sooooooooo upset if I were in your shoes. I know how you feel about breastfeeding-I guess you could always do 2 weeks of IVs as a boost, pump to keep your milk coming-and do formula for those few weeks, and just go right back to the breast after. If the doc is saying you should go on ivs, you probably should. Now isn't the time to get sick. I know you know all this-just reminding you, yeah this totally sucks...but its not the end of the world, it will be ok. It will work out.

Sorry I'm not science people.
 

Scarlett81

New member
Wow I'm really sorry you are in this lousy situation right now.
Just wanted to say that-I have no clue about the rest. I guess it would seem logical that you picked it up in the clinic or hosp. Where else would you get it?!

Are they sure you are resistant to tobi? Have you tried Tobi yet? You know they thought once I was resistant to Augmentin and then my new doc tried it, b/c she had a theory that it wasn't true, and she was right. This was years back so I can't explain the facts in scientific terms to you, sorry. Just a thought. They aren't always right.

wow, I wish I could say something to help you! I'd be sooooooooo upset if I were in your shoes. I know how you feel about breastfeeding-I guess you could always do 2 weeks of IVs as a boost, pump to keep your milk coming-and do formula for those few weeks, and just go right back to the breast after. If the doc is saying you should go on ivs, you probably should. Now isn't the time to get sick. I know you know all this-just reminding you, yeah this totally sucks...but its not the end of the world, it will be ok. It will work out.

Sorry I'm not science people.
 

Scarlett81

New member
Wow I'm really sorry you are in this lousy situation right now.
Just wanted to say that-I have no clue about the rest. I guess it would seem logical that you picked it up in the clinic or hosp. Where else would you get it?!

Are they sure you are resistant to tobi? Have you tried Tobi yet? You know they thought once I was resistant to Augmentin and then my new doc tried it, b/c she had a theory that it wasn't true, and she was right. This was years back so I can't explain the facts in scientific terms to you, sorry. Just a thought. They aren't always right.

wow, I wish I could say something to help you! I'd be sooooooooo upset if I were in your shoes. I know how you feel about breastfeeding-I guess you could always do 2 weeks of IVs as a boost, pump to keep your milk coming-and do formula for those few weeks, and just go right back to the breast after. If the doc is saying you should go on ivs, you probably should. Now isn't the time to get sick. I know you know all this-just reminding you, yeah this totally sucks...but its not the end of the world, it will be ok. It will work out.

Sorry I'm not science people.
 

ihatecf

New member
Here comes my role to explain this as I have studied microbiology along with bacteriolgy in adition to my cf experience. I'll try to make it simple.

Some germs are already naturally resistant to certain antibiotics without being exposed to them. You dont necessary have to take an antibiotic to develop resistance to it. This explains the existence of MRSA which is different to SA. Though a person acquiring MRSA may have never been exposed to the Methicilin group of antibiotics.

Pseudomonas aeruginosa comes in multiple strains. Some are mucoid and hard to treat others are sensitive to all antibiotic groups.

Tobi can be used with another sensitive antibiotic despite it being resistant. When all antibiotics become resistant you would still use them bcz when u attack pseudomnas on multi levels( aminoglycoside+3rd generation cephalosporin + beta lactam) even if all resistant they could still obtain a result.

Bacteria evolve in nature thats why science is afraid that one day all our antibiotics would be useless. I hope I helped.
 

ihatecf

New member
Here comes my role to explain this as I have studied microbiology along with bacteriolgy in adition to my cf experience. I'll try to make it simple.

Some germs are already naturally resistant to certain antibiotics without being exposed to them. You dont necessary have to take an antibiotic to develop resistance to it. This explains the existence of MRSA which is different to SA. Though a person acquiring MRSA may have never been exposed to the Methicilin group of antibiotics.

Pseudomonas aeruginosa comes in multiple strains. Some are mucoid and hard to treat others are sensitive to all antibiotic groups.

Tobi can be used with another sensitive antibiotic despite it being resistant. When all antibiotics become resistant you would still use them bcz when u attack pseudomnas on multi levels( aminoglycoside+3rd generation cephalosporin + beta lactam) even if all resistant they could still obtain a result.

Bacteria evolve in nature thats why science is afraid that one day all our antibiotics would be useless. I hope I helped.
 

ihatecf

New member
Here comes my role to explain this as I have studied microbiology along with bacteriolgy in adition to my cf experience. I'll try to make it simple.

Some germs are already naturally resistant to certain antibiotics without being exposed to them. You dont necessary have to take an antibiotic to develop resistance to it. This explains the existence of MRSA which is different to SA. Though a person acquiring MRSA may have never been exposed to the Methicilin group of antibiotics.

Pseudomonas aeruginosa comes in multiple strains. Some are mucoid and hard to treat others are sensitive to all antibiotic groups.

Tobi can be used with another sensitive antibiotic despite it being resistant. When all antibiotics become resistant you would still use them bcz when u attack pseudomnas on multi levels( aminoglycoside+3rd generation cephalosporin + beta lactam) even if all resistant they could still obtain a result.

Bacteria evolve in nature thats why science is afraid that one day all our antibiotics would be useless. I hope I helped.
 

LouLou

New member
off topic but just wanted to say that hollycathryn did IV meds while breastfeeding. She even forced the hospital to allow her daughter to stay 24-7 with her at the hospital. Are you sure none of those IV drugs are listed as okay in Medications and Mothers' Milk?
 

LouLou

New member
off topic but just wanted to say that hollycathryn did IV meds while breastfeeding. She even forced the hospital to allow her daughter to stay 24-7 with her at the hospital. Are you sure none of those IV drugs are listed as okay in Medications and Mothers' Milk?
 

LouLou

New member
off topic but just wanted to say that hollycathryn did IV meds while breastfeeding. She even forced the hospital to allow her daughter to stay 24-7 with her at the hospital. Are you sure none of those IV drugs are listed as okay in Medications and Mothers' Milk?
 

EnergyGal

New member
Thank you Rami. GREAT explantation.

If I were Wanderlost, I would be doing extra therapies to see if I could knock down the strain myself. I have in the past and after two weeks of intensive extra therapy, I cleared up my lungs.
 

EnergyGal

New member
Thank you Rami. GREAT explantation.

If I were Wanderlost, I would be doing extra therapies to see if I could knock down the strain myself. I have in the past and after two weeks of intensive extra therapy, I cleared up my lungs.
 
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