PA

I

Imogene

Administrator
A question for you from another thread..

I am probably in the wrong place. If so, and my posting is inappropriate, moderator, please delete me, or, if you can, direct me to somewhere else.

I was looking for a forum directly concerned with pseudomonas, and can't find such an animal. This is the closest I've come, and a very fine CF forum it is. My compliments to all the members and moderators. But I don't have CF.

I am a 71 year old male with COPD (chronic obstructive lung disease) for which there are many forums--in fact I'm the moderator on one of them--but pseudo., or p..a., as you folks have it, is not all that common on those forums; or if it is no one is talking about it.

I picked up p/a during a hospitalization for pneumonia in 2003. I took TOBI for a couple of months and slowly got better, though even at baseline my breathing was severely impaired (FEV1 of about a liter, or 30%). I have been as low as 15% during other exacerbations. I was also hospitalized with some of these, and in addition to broad spectrums was given Zosyn and Tobramycin to suppress the p.a.

This time I've taken TOBI for 28 days and have encountered resistance, and my pulmonologist has switched me to colistin. I've been on the colistin for a week and it doesn't seem to be doing anything either. I'm to to stay on it for a month. If it doesn;t work it's been suggested I go to a PICC line nd various other IVs.

From the posts I've read here there are other antibiotic options. Can I assume that one just works their way through these in time? Does the colistin take a while to "work" or can I assume resistance after a certain period of time?

Again I'm sorry if I've broken the rules here, but any sort of reply would be most appreciated. Thanks.

John o
 
I

Imogene

Administrator
A question for you from another thread..

I am probably in the wrong place. If so, and my posting is inappropriate, moderator, please delete me, or, if you can, direct me to somewhere else.

I was looking for a forum directly concerned with pseudomonas, and can't find such an animal. This is the closest I've come, and a very fine CF forum it is. My compliments to all the members and moderators. But I don't have CF.

I am a 71 year old male with COPD (chronic obstructive lung disease) for which there are many forums--in fact I'm the moderator on one of them--but pseudo., or p..a., as you folks have it, is not all that common on those forums; or if it is no one is talking about it.

I picked up p/a during a hospitalization for pneumonia in 2003. I took TOBI for a couple of months and slowly got better, though even at baseline my breathing was severely impaired (FEV1 of about a liter, or 30%). I have been as low as 15% during other exacerbations. I was also hospitalized with some of these, and in addition to broad spectrums was given Zosyn and Tobramycin to suppress the p.a.

This time I've taken TOBI for 28 days and have encountered resistance, and my pulmonologist has switched me to colistin. I've been on the colistin for a week and it doesn't seem to be doing anything either. I'm to to stay on it for a month. If it doesn;t work it's been suggested I go to a PICC line nd various other IVs.

From the posts I've read here there are other antibiotic options. Can I assume that one just works their way through these in time? Does the colistin take a while to "work" or can I assume resistance after a certain period of time?

Again I'm sorry if I've broken the rules here, but any sort of reply would be most appreciated. Thanks.

John o
 
I

Imogene

Administrator
A question for you from another thread..

I am probably in the wrong place. If so, and my posting is inappropriate, moderator, please delete me, or, if you can, direct me to somewhere else.

I was looking for a forum directly concerned with pseudomonas, and can't find such an animal. This is the closest I've come, and a very fine CF forum it is. My compliments to all the members and moderators. But I don't have CF.

I am a 71 year old male with COPD (chronic obstructive lung disease) for which there are many forums--in fact I'm the moderator on one of them--but pseudo., or p..a., as you folks have it, is not all that common on those forums; or if it is no one is talking about it.

I picked up p/a during a hospitalization for pneumonia in 2003. I took TOBI for a couple of months and slowly got better, though even at baseline my breathing was severely impaired (FEV1 of about a liter, or 30%). I have been as low as 15% during other exacerbations. I was also hospitalized with some of these, and in addition to broad spectrums was given Zosyn and Tobramycin to suppress the p.a.

This time I've taken TOBI for 28 days and have encountered resistance, and my pulmonologist has switched me to colistin. I've been on the colistin for a week and it doesn't seem to be doing anything either. I'm to to stay on it for a month. If it doesn;t work it's been suggested I go to a PICC line nd various other IVs.

From the posts I've read here there are other antibiotic options. Can I assume that one just works their way through these in time? Does the colistin take a while to "work" or can I assume resistance after a certain period of time?

Again I'm sorry if I've broken the rules here, but any sort of reply would be most appreciated. Thanks.

John o
 
I

Imogene

Administrator
A question for you from another thread..

I am probably in the wrong place. If so, and my posting is inappropriate, moderator, please delete me, or, if you can, direct me to somewhere else.

I was looking for a forum directly concerned with pseudomonas, and can't find such an animal. This is the closest I've come, and a very fine CF forum it is. My compliments to all the members and moderators. But I don't have CF.

I am a 71 year old male with COPD (chronic obstructive lung disease) for which there are many forums--in fact I'm the moderator on one of them--but pseudo., or p..a., as you folks have it, is not all that common on those forums; or if it is no one is talking about it.

I picked up p/a during a hospitalization for pneumonia in 2003. I took TOBI for a couple of months and slowly got better, though even at baseline my breathing was severely impaired (FEV1 of about a liter, or 30%). I have been as low as 15% during other exacerbations. I was also hospitalized with some of these, and in addition to broad spectrums was given Zosyn and Tobramycin to suppress the p.a.

This time I've taken TOBI for 28 days and have encountered resistance, and my pulmonologist has switched me to colistin. I've been on the colistin for a week and it doesn't seem to be doing anything either. I'm to to stay on it for a month. If it doesn;t work it's been suggested I go to a PICC line nd various other IVs.

From the posts I've read here there are other antibiotic options. Can I assume that one just works their way through these in time? Does the colistin take a while to "work" or can I assume resistance after a certain period of time?

Again I'm sorry if I've broken the rules here, but any sort of reply would be most appreciated. Thanks.

John o
 
I

Imogene

Administrator
A question for you from another thread..
<br />
<br />I am probably in the wrong place. If so, and my posting is inappropriate, moderator, please delete me, or, if you can, direct me to somewhere else.
<br />
<br />I was looking for a forum directly concerned with pseudomonas, and can't find such an animal. This is the closest I've come, and a very fine CF forum it is. My compliments to all the members and moderators. But I don't have CF.
<br />
<br />I am a 71 year old male with COPD (chronic obstructive lung disease) for which there are many forums--in fact I'm the moderator on one of them--but pseudo., or p..a., as you folks have it, is not all that common on those forums; or if it is no one is talking about it.
<br />
<br />I picked up p/a during a hospitalization for pneumonia in 2003. I took TOBI for a couple of months and slowly got better, though even at baseline my breathing was severely impaired (FEV1 of about a liter, or 30%). I have been as low as 15% during other exacerbations. I was also hospitalized with some of these, and in addition to broad spectrums was given Zosyn and Tobramycin to suppress the p.a.
<br />
<br />This time I've taken TOBI for 28 days and have encountered resistance, and my pulmonologist has switched me to colistin. I've been on the colistin for a week and it doesn't seem to be doing anything either. I'm to to stay on it for a month. If it doesn;t work it's been suggested I go to a PICC line nd various other IVs.
<br />
<br />From the posts I've read here there are other antibiotic options. Can I assume that one just works their way through these in time? Does the colistin take a while to "work" or can I assume resistance after a certain period of time?
<br />
<br />Again I'm sorry if I've broken the rules here, but any sort of reply would be most appreciated. Thanks.
<br />
<br />John o
 
J

JazzysMom

New member
IT really varies. The best thing that can be done is for you to provide a sputum culture & allow them to do a sensitivity test on it.

This will show them which antibiotics work & how well on YOUR PA since everyone can be different. There is a chance that you have a different strain of PA that wont allow the meds to work OR it is just plain old resistant to it.

Sorry to hear of your fight....

The meds I have used over the years for my PA is:

IV: Tobra, Zosyn, Merepenem & Cefepieme
ORAL: Cipro
NEBS: Colistin, Tobi

If you have other ?? let us know, but I hope this helps some. The other group of people I know that culture PA is HIV patients!
 
J

JazzysMom

New member
IT really varies. The best thing that can be done is for you to provide a sputum culture & allow them to do a sensitivity test on it.

This will show them which antibiotics work & how well on YOUR PA since everyone can be different. There is a chance that you have a different strain of PA that wont allow the meds to work OR it is just plain old resistant to it.

Sorry to hear of your fight....

The meds I have used over the years for my PA is:

IV: Tobra, Zosyn, Merepenem & Cefepieme
ORAL: Cipro
NEBS: Colistin, Tobi

If you have other ?? let us know, but I hope this helps some. The other group of people I know that culture PA is HIV patients!
 
J

JazzysMom

New member
IT really varies. The best thing that can be done is for you to provide a sputum culture & allow them to do a sensitivity test on it.

This will show them which antibiotics work & how well on YOUR PA since everyone can be different. There is a chance that you have a different strain of PA that wont allow the meds to work OR it is just plain old resistant to it.

Sorry to hear of your fight....

The meds I have used over the years for my PA is:

IV: Tobra, Zosyn, Merepenem & Cefepieme
ORAL: Cipro
NEBS: Colistin, Tobi

If you have other ?? let us know, but I hope this helps some. The other group of people I know that culture PA is HIV patients!
 
J

JazzysMom

New member
IT really varies. The best thing that can be done is for you to provide a sputum culture & allow them to do a sensitivity test on it.

This will show them which antibiotics work & how well on YOUR PA since everyone can be different. There is a chance that you have a different strain of PA that wont allow the meds to work OR it is just plain old resistant to it.

Sorry to hear of your fight....

The meds I have used over the years for my PA is:

IV: Tobra, Zosyn, Merepenem & Cefepieme
ORAL: Cipro
NEBS: Colistin, Tobi

If you have other ?? let us know, but I hope this helps some. The other group of people I know that culture PA is HIV patients!
 
J

JazzysMom

New member
IT really varies. The best thing that can be done is for you to provide a sputum culture & allow them to do a sensitivity test on it.
<br />
<br />This will show them which antibiotics work & how well on YOUR PA since everyone can be different. There is a chance that you have a different strain of PA that wont allow the meds to work OR it is just plain old resistant to it.
<br />
<br />Sorry to hear of your fight....
<br />
<br />The meds I have used over the years for my PA is:
<br />
<br />IV: Tobra, Zosyn, Merepenem & Cefepieme
<br />ORAL: Cipro
<br />NEBS: Colistin, Tobi
<br />
<br />If you have other ?? let us know, but I hope this helps some. The other group of people I know that culture PA is HIV patients!
 
F

folione

New member
Colistin is supposedly a drug that bugs do not become resistant to because of something to do with how it kills the bugs. BUT, my son has tried it 3 or 4 times and it never seems to be all that effective for him. The drugs available for pseudomonas via nebulizer are pretty limited but you might want to ask if you can get on the program to use inhaled Aztreonam - it is a pre-approval med for CF pseudomonas treatment and I get the impression certain patients with a need & limited options can get it even though FDA has not passed it yet. Otherwise, the IV stuff comes in tons of varieties and one of them is almost certain to do the trick.
 
F

folione

New member
Colistin is supposedly a drug that bugs do not become resistant to because of something to do with how it kills the bugs. BUT, my son has tried it 3 or 4 times and it never seems to be all that effective for him. The drugs available for pseudomonas via nebulizer are pretty limited but you might want to ask if you can get on the program to use inhaled Aztreonam - it is a pre-approval med for CF pseudomonas treatment and I get the impression certain patients with a need & limited options can get it even though FDA has not passed it yet. Otherwise, the IV stuff comes in tons of varieties and one of them is almost certain to do the trick.
 
F

folione

New member
Colistin is supposedly a drug that bugs do not become resistant to because of something to do with how it kills the bugs. BUT, my son has tried it 3 or 4 times and it never seems to be all that effective for him. The drugs available for pseudomonas via nebulizer are pretty limited but you might want to ask if you can get on the program to use inhaled Aztreonam - it is a pre-approval med for CF pseudomonas treatment and I get the impression certain patients with a need & limited options can get it even though FDA has not passed it yet. Otherwise, the IV stuff comes in tons of varieties and one of them is almost certain to do the trick.
 
F

folione

New member
Colistin is supposedly a drug that bugs do not become resistant to because of something to do with how it kills the bugs. BUT, my son has tried it 3 or 4 times and it never seems to be all that effective for him. The drugs available for pseudomonas via nebulizer are pretty limited but you might want to ask if you can get on the program to use inhaled Aztreonam - it is a pre-approval med for CF pseudomonas treatment and I get the impression certain patients with a need & limited options can get it even though FDA has not passed it yet. Otherwise, the IV stuff comes in tons of varieties and one of them is almost certain to do the trick.
 
F

folione

New member
Colistin is supposedly a drug that bugs do not become resistant to because of something to do with how it kills the bugs. BUT, my son has tried it 3 or 4 times and it never seems to be all that effective for him. The drugs available for pseudomonas via nebulizer are pretty limited but you might want to ask if you can get on the program to use inhaled Aztreonam - it is a pre-approval med for CF pseudomonas treatment and I get the impression certain patients with a need & limited options can get it even though FDA has not passed it yet. Otherwise, the IV stuff comes in tons of varieties and one of them is almost certain to do the trick.
 
M

MicheleGazelle

New member
I've never had PA. What I know about it can be found here:

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/quinineandpseudomonas.shtml">http://healthgazelle.org/quinineandpseudomonas.shtml</a>

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/magnesiumandazythromycin.shtml">http://healthgazelle.org/magnesiumandazythromycin.shtml</a>
 
M

MicheleGazelle

New member
I've never had PA. What I know about it can be found here:

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/quinineandpseudomonas.shtml">http://healthgazelle.org/quinineandpseudomonas.shtml</a>

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/magnesiumandazythromycin.shtml">http://healthgazelle.org/magnesiumandazythromycin.shtml</a>
 
M

MicheleGazelle

New member
I've never had PA. What I know about it can be found here:

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/quinineandpseudomonas.shtml">http://healthgazelle.org/quinineandpseudomonas.shtml</a>

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/magnesiumandazythromycin.shtml">http://healthgazelle.org/magnesiumandazythromycin.shtml</a>
 
M

MicheleGazelle

New member
I've never had PA. What I know about it can be found here:

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/quinineandpseudomonas.shtml">http://healthgazelle.org/quinineandpseudomonas.shtml</a>

<a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/magnesiumandazythromycin.shtml">http://healthgazelle.org/magnesiumandazythromycin.shtml</a>
 
M

MicheleGazelle

New member
I've never had PA. What I know about it can be found here:
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/quinineandpseudomonas.shtml">http://healthgazelle.org/quinineandpseudomonas.shtml</a>
<br />
<br /><a target=_blank class=ftalternatingbarlinklarge href="http://healthgazelle.org/magnesiumandazythromycin.shtml">http://healthgazelle.org/magnesiumandazythromycin.shtml</a>
 
You must log in or register to reply here.
Top