My daughter, who is 12, has been having a lot of pain in her legs. It mainly is a little above the knee down to her feet. I was wondering if anyone else has had this kind of problem? It gets bad enough that I give ibuprofen and it helps. The doctor ran an ana test, and it came back positive. So, now he is running some more test. My question is, has anyone else with cf had this kind of problem? Could this be cf related or something else. What causes a positive ana. I know that lupus can, but what else