I take Creon 10. About 4-6 with meals.. Usually 4 with snacks. There are some things that are always rough on my tummy, such as peanut butter and mexican food, so I always take a little extra with stuff like that. <br><br>On a side note...A long time ago, my dad's insurance only approved some generic kind, which wasn't even a direct equivelent of Creon... I took about 25 with a meal..and I still pooped myself to death! My chest broke out in a really bad rash. I think I was in eleventh grade, so everyone thought I had hickies. (That was the only funny part of the story.) I remember waking up in the night just clawing at my chest, it itched sooooo badly... Doctor ended up writing a letter to insurance co explaining why I HAD to have Creon. I was glad when all that was over. I think my dr even said that some of those generic enzymes don't even have to follow same rules as the name brand ones. Anyways, just thought I'd share.