Hi - I had a chemical pleurodesis done 4 years ago following a lung collapse. I was 24 at the time. It was my first/only lung collapse, also spontaneous, and very collapsed. They tried chest tubes for about 10 days before deciding to do the procedure, as my lung was just not "re-sticking" as it needed to. I got a second opinion during this time from another lung surgeon outside my CF clinic, at the recommendation of my CF doc, who agreed this was the right thing to do. IR did the actual procedure at my CF hospital.
I have not had any lung collapses since then, so the procedure seems to have done the trick. That said, it was very painful, as were the chest tubes. It hurt quite a lot to move, especially anything involving core strength (e.g. going from laying down to sitting up). I had one night in the hospital following the procedure before going home - was on IV Dilaudid in the hospital, and then I went home with oxycodone for a few days. Despite a lot of pain the first few days, I recovered pretty quickly. I was back to work two weeks later, and it overall took a few weeks to re-condition myself to activity/exercise. I think I started using my vest again about a week after the procedure, but I don't recall exactly - and I was on antibiotics the whole time to offset the possibility of an exacerbation, since I wasn't able to do much chest PT through all of this. Fortunately, I did not lose any lung function long-term from this and haven't had any lingering effects. As a strange added benefit: I used to have hemoptysis often from a certain spot in my left lung. Since the pneumo and pleurodesis, I haven't had any bleeds from that spot. My theory is that the collapse kind of re-arranged/re-booted things in that area and sealed off the vessel that was problematic.
I hope everything went well for your son this morning and that he recovers quickly!