I use to use Advair, but really didnt think it did much good. I will also say that during the time I was using it I was having extreme problems with my airways & its possible I wasnt able to get all the powder as deep as I needed to. I have been on Pulmicort since & love it. I prefer nebs because it seems to get in deeper to my lungs. I have been on Pulmicort for about a year now. I also take Zithromax for its antiinflammatory agents.