Emily is almost 5 and has been on both HTS and Pulmozyme since she was very young. I can't remember exactly right now, but I'll guess she was under 18 months when starting both.
She just finished the ISIS clinical trial for HTS, and resumed 7% HTS. We are fairly certain that she did not have the "real" thing dudring the year of the trial. I thought that resuming it would be rough, but it hasn't been too bad.
Right now, we do HTS 2x/daily and Pulmozyme 1x. Prior to both, we do albuterol MDI.