Question about CF'ers and alcohol

[Havoc]

Alcohol wipes= isopropanol
<br />Drinking alcohol= ethanol
<br />
<br />You are partially correct, in that some people, often linked with Asian heritage, have a reaction to acetaldehyde due to a lack of the enzyme aldehyde dehydrogenase. Certain antibiotics and antifungals can inhibit aldehyde dehydrogenase (which I generically and anecdotally stated in my earlier post for convenience).
<br />
<br />Alcohol is a poison, the body can metabolize ethanol, methanol on the other hand will kill you (or at the very least make you go blind). In a case where one is deficient in ALDH (either from a genetic mutation or inhibited by a medication), ethanol cannot be converted to acetic acid as readily and the result is an immunological response which is similar to an allergic reaction.
<br />
<br />There is some evidence that H2 blockers can reduce this reaction, but they also tend to greatly increase BAL through an unknown mechanism.
<br />
<br />CF's relationship with alcohol is that it's metabolized in the liver on the P450 cytochrome. People with CF tend to have more efficient metabolism on the P450, which means we tend to have a better tolerance for caffeine, alcohol, benzodiazepines, narcotics, amiodarone (anything metabolized on the P450) etc.
<br />
<br />I realize I'll probably catch hell for this post. It's not my intention to make people feel badly, but I feel I have to clarify when I see misinformation, or just guesswork, in a reply where someone is seeking information.

 

[ej0820]

@ Havoc: I admire the scientific nerd in you (please do not be offended that I called you a nerd <img src="i/expressions/face-icon-small-smile.gif" border="0"> ). As a biologist myself, I love all of your posts and learn a lot from them! I had no idea we CFers tend to have a better tolerance for caffeine, alcohol and narcotics (and for the reason you mentioned)...you couldn't prove it by me, ha! I imagine abx can counter that effect at varying degrees, though.

To the OP, I've never gotten hives from drinking alcohol, but like Havoc, I've been flushed and had a hot face after drinking alcohol (I'm talking drinks I've had before that never caused a problem) while on certain abx. Bactrim and Doxycycline come to mind, though it hasn't happened in quite some time and I haven't been on either of those for even longer. Sorry if I'm not much help. Antibiotics can do crazy things sometimes...

 

[ej0820]

@ Havoc: I admire the scientific nerd in you (please do not be offended that I called you a nerd <img src="i/expressions/face-icon-small-smile.gif" border="0"> ). As a biologist myself, I love all of your posts and learn a lot from them! I had no idea we CFers tend to have a better tolerance for caffeine, alcohol and narcotics (and for the reason you mentioned)...you couldn't prove it by me, ha! I imagine abx can counter that effect at varying degrees, though.

To the OP, I've never gotten hives from drinking alcohol, but like Havoc, I've been flushed and had a hot face after drinking alcohol (I'm talking drinks I've had before that never caused a problem) while on certain abx. Bactrim and Doxycycline come to mind, though it hasn't happened in quite some time and I haven't been on either of those for even longer. Sorry if I'm not much help. Antibiotics can do crazy things sometimes...

 

[ej0820]

@ Havoc: I admire the scientific nerd in you (please do not be offended that I called you a nerd <img src="i/expressions/face-icon-small-smile.gif" border="0"> ). As a biologist myself, I love all of your posts and learn a lot from them! I had no idea we CFers tend to have a better tolerance for caffeine, alcohol and narcotics (and for the reason you mentioned)...you couldn't prove it by me, ha! I imagine abx can counter that effect at varying degrees, though.
<br />
<br />To the OP, I've never gotten hives from drinking alcohol, but like Havoc, I've been flushed and had a hot face after drinking alcohol (I'm talking drinks I've had before that never caused a problem) while on certain abx. Bactrim and Doxycycline come to mind, though it hasn't happened in quite some time and I haven't been on either of those for even longer. Sorry if I'm not much help. Antibiotics can do crazy things sometimes...

 

[Havoc]

Heh, no offense taken. I know I'm a huge nerd <img src="i/expressions/face-icon-small-smile.gif" border="0">

 

[Havoc]

Heh, no offense taken. I know I'm a huge nerd <img src="i/expressions/face-icon-small-smile.gif" border="0">

 

[Havoc]

Heh, no offense taken. I know I'm a huge nerd <img src="i/expressions/face-icon-small-smile.gif" border="0">

 

[static]

<div class="FTQUOTE"><begin quote>I realize I'll probably catch hell for this post.</end quote></div>

I don't see why.

<div class="FTQUOTE"><begin quote>when I see misinformation, or just guesswork, in a reply where someone is seeking information</end quote></div>

Oh ok. Personally I don't see a problem in correcting someone. There is so much information out there, even from conflicting "expert" sources, that it is easy to get stuff mixed up (I admit I do from time to time). However, calling it "guesswork" may be a little harsh. It might also be helpful to give your sources for members to compare, but that is up to you.

Anyways now that the "hell" is over with (just a little humor) I would like to share my own experiences with this issue.

I think last new years a few friends came over and we played some drinking games. A few of them were asian and I did see first-hand that redness you guys were talking about. His explination was it was part of the asian-heritage as well. Since it was my first time ever really drinking I was planning on taking it slow, however by the end of the night I was able to beat almost all my friends without feeling drunk at all. They all thought I was "cool" (expecially the few military people, drinking was really big with them). For whatever reason the next morning I decided to email my doctor to see if drinking was ok for someone with cf, since I seemed to tolerate it so well. He gave me a list of reasons why it wasn't a good idea to drink (I can't remember it off the top of my head), but didn't directly tell me to stop. I guess it scared me off though, because I haven't really drank since.

I know the 20s are usually a party phase and I am somewhat upset I am missing out on that, but I figure my health is more important right now (and the vodka tastes exactly like scope mouth wash to me, just sayin').

 

[static]

<div class="FTQUOTE"><begin quote>I realize I'll probably catch hell for this post.</end quote>

I don't see why.

<div class="FTQUOTE"><begin quote>when I see misinformation, or just guesswork, in a reply where someone is seeking information</end quote>

Oh ok. Personally I don't see a problem in correcting someone. There is so much information out there, even from conflicting "expert" sources, that it is easy to get stuff mixed up (I admit I do from time to time). However, calling it "guesswork" may be a little harsh. It might also be helpful to give your sources for members to compare, but that is up to you.

Anyways now that the "hell" is over with (just a little humor) I would like to share my own experiences with this issue.

I think last new years a few friends came over and we played some drinking games. A few of them were asian and I did see first-hand that redness you guys were talking about. His explination was it was part of the asian-heritage as well. Since it was my first time ever really drinking I was planning on taking it slow, however by the end of the night I was able to beat almost all my friends without feeling drunk at all. They all thought I was "cool" (expecially the few military people, drinking was really big with them). For whatever reason the next morning I decided to email my doctor to see if drinking was ok for someone with cf, since I seemed to tolerate it so well. He gave me a list of reasons why it wasn't a good idea to drink (I can't remember it off the top of my head), but didn't directly tell me to stop. I guess it scared me off though, because I haven't really drank since.

I know the 20s are usually a party phase and I am somewhat upset I am missing out on that, but I figure my health is more important right now (and the vodka tastes exactly like scope mouth wash to me, just sayin').

 

[static]

<div class="FTQUOTE"><begin quote>I realize I'll probably catch hell for this post.</end quote>
<br />
<br />I don't see why.
<br />
<br /><div class="FTQUOTE"><begin quote>when I see misinformation, or just guesswork, in a reply where someone is seeking information</end quote>
<br />
<br />Oh ok. Personally I don't see a problem in correcting someone. There is so much information out there, even from conflicting "expert" sources, that it is easy to get stuff mixed up (I admit I do from time to time). However, calling it "guesswork" may be a little harsh. It might also be helpful to give your sources for members to compare, but that is up to you.
<br />
<br />Anyways now that the "hell" is over with (just a little humor) I would like to share my own experiences with this issue.
<br />
<br />I think last new years a few friends came over and we played some drinking games. A few of them were asian and I did see first-hand that redness you guys were talking about. His explination was it was part of the asian-heritage as well. Since it was my first time ever really drinking I was planning on taking it slow, however by the end of the night I was able to beat almost all my friends without feeling drunk at all. They all thought I was "cool" (expecially the few military people, drinking was really big with them). For whatever reason the next morning I decided to email my doctor to see if drinking was ok for someone with cf, since I seemed to tolerate it so well. He gave me a list of reasons why it wasn't a good idea to drink (I can't remember it off the top of my head), but didn't directly tell me to stop. I guess it scared me off though, because I haven't really drank since.
<br />
<br />I know the 20s are usually a party phase and I am somewhat upset I am missing out on that, but I figure my health is more important right now (and the vodka tastes exactly like scope mouth wash to me, just sayin').

 

[xin]

<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>static</b></i>
I know the 20s are usually a party phase and I am somewhat upset I am missing out on that...</end quote></div>

It's funny - I just had a chat with my neighbor about this yesterday over a couple pints of Guinness. Ages 17 - 20 was my party phase. Upon turning 21 (and legal) I suddenly lost interest and began partying significantly less.

But I digress, and now I'm OT.

To the OP: my feeling is the folks who have suggested an allergic reaction are probably correct. But <i>whatever</i> the cause was, I think it should be a pretty simple fix. Don't drink Jager. The %#$@ is terrible anyway.

 

[xin]

<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>static</b></i>
I know the 20s are usually a party phase and I am somewhat upset I am missing out on that...</end quote>

It's funny - I just had a chat with my neighbor about this yesterday over a couple pints of Guinness. Ages 17 - 20 was my party phase. Upon turning 21 (and legal) I suddenly lost interest and began partying significantly less.

But I digress, and now I'm OT.

To the OP: my feeling is the folks who have suggested an allergic reaction are probably correct. But <i>whatever</i> the cause was, I think it should be a pretty simple fix. Don't drink Jager. The %#$@ is terrible anyway.

 

[xin]

<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>static</b></i>
<br />I know the 20s are usually a party phase and I am somewhat upset I am missing out on that...</end quote>
<br />
<br />It's funny - I just had a chat with my neighbor about this yesterday over a couple pints of Guinness. Ages 17 - 20 was my party phase. Upon turning 21 (and legal) I suddenly lost interest and began partying significantly less.
<br />
<br />But I digress, and now I'm OT.
<br />
<br />To the OP: my feeling is the folks who have suggested an allergic reaction are probably correct. But <i>whatever</i> the cause was, I think it should be a pretty simple fix. Don't drink Jager. The %#$@ is terrible anyway.

 

[giantsfan91]

Thanks for all the input everyone! I'll just have to stay away from it.

 

[giantsfan91]

Thanks for all the input everyone! I'll just have to stay away from it.

 

[giantsfan91]

Thanks for all the input everyone! I'll just have to stay away from it.

 

[mamaScarlett]

Yes you can have allergic reaction to components of alcohol. I have mild allergies to sulfites so I can't have wine with sulfites in it. The same goes for some sulfa drugs.

 

[mamaScarlett]

Yes you can have allergic reaction to components of alcohol. I have mild allergies to sulfites so I can't have wine with sulfites in it. The same goes for some sulfa drugs.

 

[mamaScarlett]

Yes you can have allergic reaction to components of alcohol. I have mild allergies to sulfites so I can't have wine with sulfites in it. The same goes for some sulfa drugs.