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Question
- Thread starter LeftY
- Start date
cfcndlelady
New member
BOTH parents have to be a carrier! So if you have CF and your hubby isn't a carrier then your child won't have CF but could be a carrier!
Caren 34 W/CF
Caren 34 W/CF
thre's a difference between having CF or being a carrier of the CF gene.
Your parents were both CF gene carriers. So you had a 1/4 chance of getting CF.
If your husband does not carry the CF gene ( like your parents), you have % chance of having a kid with CF. If you husband does carry the CF, you have a 50% chance of having a kid with CF.
Your parents were both CF gene carriers. So you had a 1/4 chance of getting CF.
If your husband does not carry the CF gene ( like your parents), you have % chance of having a kid with CF. If you husband does carry the CF, you have a 50% chance of having a kid with CF.
One one partner has CF and the other does not... there are two possible scenarios.
The non-CF parent needs to undergo genetic testing to detemine their carrier status. There are a number of posts about it, with Ambry and Quest having the most extensive tests. These tests aren't perfect, especially so with the tests that only look for the most common mutations. The below examples are in a perfect world.
CF parent (two CF genes, has CF) and a Carrier Parent (one CF gene, no CF)
50% chance of a child with CF (two CF genes)
50% chance of a child that is a carrier (one CF gene, no CF)
CF parent (two CF genes, has CF) and a non-carrier Parent (no CF genes, no CF)
100% chance of a child that is a carrier (one CF gene).
There are four other possible scenarios:
CF parent (two CF genes, has CF) and a CF parent (two CF genes, has CF)
100% chance of a child with CF (two CF genes)
Carrier Parent (one CF gene, no CF) and a Carrier Parent (one CF gene, no CF)
25% chance for a non-carrier child (no CF genes, no CF)
50% chance of a child that is a carrier (one CF gene, no CF)
25% chance of a child with CF (two CF genes)
Carrier Parent (one CF gene, no CF) and a non-carrier Parent (no CF genes, no CF)
75% chance for a non-carrier child (no CF genes, no CF)
25% chance of a child that is a carrier (one CF gene, no CF)
Non-carrier Parent (no CF genes, no CF) and a non-carrier Parent (no CF genes, no CF)
100% chance for a non-carrier child (no CF genes, no CF)
The non-CF parent needs to undergo genetic testing to detemine their carrier status. There are a number of posts about it, with Ambry and Quest having the most extensive tests. These tests aren't perfect, especially so with the tests that only look for the most common mutations. The below examples are in a perfect world.
CF parent (two CF genes, has CF) and a Carrier Parent (one CF gene, no CF)
50% chance of a child with CF (two CF genes)
50% chance of a child that is a carrier (one CF gene, no CF)
CF parent (two CF genes, has CF) and a non-carrier Parent (no CF genes, no CF)
100% chance of a child that is a carrier (one CF gene).
There are four other possible scenarios:
CF parent (two CF genes, has CF) and a CF parent (two CF genes, has CF)
100% chance of a child with CF (two CF genes)
Carrier Parent (one CF gene, no CF) and a Carrier Parent (one CF gene, no CF)
25% chance for a non-carrier child (no CF genes, no CF)
50% chance of a child that is a carrier (one CF gene, no CF)
25% chance of a child with CF (two CF genes)
Carrier Parent (one CF gene, no CF) and a non-carrier Parent (no CF genes, no CF)
75% chance for a non-carrier child (no CF genes, no CF)
25% chance of a child that is a carrier (one CF gene, no CF)
Non-carrier Parent (no CF genes, no CF) and a non-carrier Parent (no CF genes, no CF)
100% chance for a non-carrier child (no CF genes, no CF)
Lefty, I have a diagram on my website that might help a bit. Miesl wrote it out perfectly but sometime it helps people to see a picture too (at least I know that I am that way). Here's the link, just click on it and you will be taken to the page with the picture on it: <a target=_blank class=ftalternatingbarlinklarge href="http://www.cysticfibrosismaleinfertility.com/Where_to_begin_carrierTesting.html
">http://www.cysticfibrosismalei...n_carrierTesting.html
</a>
Can I ask you a question? Do you have CF or does your spouse have CF? Just asking as it might be easier for us to give a more specific answer to you if we know that information. Although it seems as though you are understanding now. But don't hesitate to ask if it still doesn't make sense to you
Welcome to the website@
">http://www.cysticfibrosismalei...n_carrierTesting.html
</a>
Can I ask you a question? Do you have CF or does your spouse have CF? Just asking as it might be easier for us to give a more specific answer to you if we know that information. Although it seems as though you are understanding now. But don't hesitate to ask if it still doesn't make sense to you
Welcome to the website@
<div class="FTQUOTE"><begin quote><i>Originally posted by: <b>julie</b></i> Lefty, I have a
diagram on my website that might help a bit. Miesl wrote it out
perfectly but sometime it helps people to see a picture too (at
least I know that I am that way). Here's the link, just click on it
and you will be taken to the page with the picture on it:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.cysticfibrosismaleinfertility.com/Where_to_begin_carrierTesting.html
">http://www.cysticfibrosismalei..._carrierTesting.html
</a> Can I ask you a question? Do you have CF or does your spouse
have CF? Just asking as it might be easier for us to give a more
specific answer to you if we know that information. Although it
seems as though you are understanding now. But don't hesitate to
ask if it still doesn't make sense to you Welcome to the
website@</end quote></div><br>
<br>
i have it...<br>
i dont know what diferences are betwen CF and CF carrier...<br>
is CF carrier have CF or he only "carry" CF?
diagram on my website that might help a bit. Miesl wrote it out
perfectly but sometime it helps people to see a picture too (at
least I know that I am that way). Here's the link, just click on it
and you will be taken to the page with the picture on it:
<a target=_blank class=ftalternatingbarlinklarge href="http://www.cysticfibrosismaleinfertility.com/Where_to_begin_carrierTesting.html
">http://www.cysticfibrosismalei..._carrierTesting.html
</a> Can I ask you a question? Do you have CF or does your spouse
have CF? Just asking as it might be easier for us to give a more
specific answer to you if we know that information. Although it
seems as though you are understanding now. But don't hesitate to
ask if it still doesn't make sense to you Welcome to the
website@</end quote></div><br>
<br>
i have it...<br>
i dont know what diferences are betwen CF and CF carrier...<br>
is CF carrier have CF or he only "carry" CF?
I can try to help explain that to you lefty.
You have CF, so you carry 2 CF mutations. One came from your mom and one came from your dad. Both of your parents are what we call "carriers". (unless one of them had CF too, but I'm assuming neither of them had CF). Your mom has 1 CF mutation and your dad has 1 CF mutation.
So, because they only have 1 CF mutation, they are considered "carriers" of the CF disease. Anybody who has just 1 CF mutation is considered a carrier.
You have 2 CF mutations, so you HAVE CF.
Hope that helps and makes sense, but if not, I can explain it again, just let me know! <img src="i/expressions/face-icon-small-smile.gif" border="0">
About the question of babies since you have CF and you have 2 CF mutations, you WILL pass 1 of those mutations onto ANY children you have.
Therefore, it is VERY important that your spouse get tested to see if they are a carrier of the CF mutation (have 1 CF mutation). The reason why is because, as stated before, your children will get 1 of your CF mutations. If your spouse is also a carrier, they risk passing their mutation onto the child as well. So if the child ends up with just 1 of your CF mutations, your child will be a carrier too. But if the child ends up with 1 of your mutations AND the 1 mutation that your spouse carries, your child WILL have CF, just as you do. The tricky/complicated thing is that there is NO way to know if the "carrier" spouse will pass on their 1 mutation. It's all about probabilities, and there's no way to know.
There are some advanced technologies that can be used if you are afraid of your child having CF (if your spouse is a carrier too). But here in the states it is expensive. I'm not sure how it works where you live. But the Procedures are called In-Vitro with PreGenetic Implantation Diagnosis (PGD). That's much more complicated than what you were asking, so I'll keep it at that.
For example, my husband has CF, and he carries 2 CF mutations. I was tested via a blood test to see if I carry an mutations and I don't have any. I am now pregnant, and our children WILL be carriers because each of them will get 1 mutation from their father.
Hope this helps and I hope I didn't confuse you more.
If I did, just speak up and maybe someone else can answer better (I tend to be a bit lengthy!!! <img src="i/expressions/face-icon-small-smile.gif" border="0">)
You have CF, so you carry 2 CF mutations. One came from your mom and one came from your dad. Both of your parents are what we call "carriers". (unless one of them had CF too, but I'm assuming neither of them had CF). Your mom has 1 CF mutation and your dad has 1 CF mutation.
So, because they only have 1 CF mutation, they are considered "carriers" of the CF disease. Anybody who has just 1 CF mutation is considered a carrier.
You have 2 CF mutations, so you HAVE CF.
Hope that helps and makes sense, but if not, I can explain it again, just let me know! <img src="i/expressions/face-icon-small-smile.gif" border="0">
About the question of babies since you have CF and you have 2 CF mutations, you WILL pass 1 of those mutations onto ANY children you have.
Therefore, it is VERY important that your spouse get tested to see if they are a carrier of the CF mutation (have 1 CF mutation). The reason why is because, as stated before, your children will get 1 of your CF mutations. If your spouse is also a carrier, they risk passing their mutation onto the child as well. So if the child ends up with just 1 of your CF mutations, your child will be a carrier too. But if the child ends up with 1 of your mutations AND the 1 mutation that your spouse carries, your child WILL have CF, just as you do. The tricky/complicated thing is that there is NO way to know if the "carrier" spouse will pass on their 1 mutation. It's all about probabilities, and there's no way to know.
There are some advanced technologies that can be used if you are afraid of your child having CF (if your spouse is a carrier too). But here in the states it is expensive. I'm not sure how it works where you live. But the Procedures are called In-Vitro with PreGenetic Implantation Diagnosis (PGD). That's much more complicated than what you were asking, so I'll keep it at that.
For example, my husband has CF, and he carries 2 CF mutations. I was tested via a blood test to see if I carry an mutations and I don't have any. I am now pregnant, and our children WILL be carriers because each of them will get 1 mutation from their father.
Hope this helps and I hope I didn't confuse you more.
If I did, just speak up and maybe someone else can answer better (I tend to be a bit lengthy!!! <img src="i/expressions/face-icon-small-smile.gif" border="0">)
i understand now... (well, i thinks so... <img src="i/expressions/face-icon-small-smile.gif" border="0"> )<br>
it's a little confusing, but it is understandable...<br>
<br>
<br>
btw, congratulations for pregnacy...<img src="i/expressions/face-icon-small-smile.gif" border="0"> <img src="i/expressions/face-icon-small-cool.gif" border="0">
it's a little confusing, but it is understandable...<br>
<br>
<br>
btw, congratulations for pregnacy...<img src="i/expressions/face-icon-small-smile.gif" border="0"> <img src="i/expressions/face-icon-small-cool.gif" border="0">