Quick question

S

New member
Does the fact that I have CF automatically make me a carrier of the CF gene? I just found out that my girlfriend and I are going to have a baby and am now in the process of starting to figure out what needs to be known. We are going in for an appointment on Tuesday for the ultrasound and for her to get a genetic screening, but I would rather get a jump on things. The biggest worry we both have is in regards to the possibility of the child having cf. We have already discussed and decided what we are going to do depending on what the CVS or amnio test shows, so now it's just time to sit and wait, I guess.
 

Emily65Roses

New member
Yes it automatically makes you a carrier of the CF gene. And your child will automatically be a carrier as well. He or she will most certainly get a CF gene from you, as those are the only genes you have to give. If your wife is a carrier, the child will have a 50% chance of having CF, and a 50% chance of being just a carrier. If she's not a carrier, you child will carry the gene, but will not have CF.
 

ERIC

New member
Hi There,
Yes having Cf does mean that you are a carrier for Cf. Your girlfriend need to be tested to see if she is a cf carrier. If she is not a cf carrier then there is nothing for you to worry about. I would have the baby tested once he/she turns 3 mths old to be sure. I decided before I finished I would look up the facts. Acoording to many books I have read it says that A Parent with Cf wil pass on a Cf gene to all of his or her children. This is because the parent with Cf has two Genes, so every sperm or egg produced will cary a Cf gene. As a result the genetic makeup of the partner will determine if the children wil have Cf. So as long as you girlfriend is not a carrier everything will be fine. if she is a carrier there is a 50% chance that the baby will be born with Cf. If you have any more questions ask them here or you can email me at k_m_0020@yahoo.com. If you wondering why I know so much my 12 yr old son has Cf and we just found out 2 and 1/2 years ago.
kandi
 

anonymous

New member
Well first off, congratulations! This might be able to give you a bit more direction to answer your question. Visit this site: <a target=new class=ftalternatingbarlinklarge href="http://www.cysticfibrosismaleinfertility.com/Before_you_begin.html.">http://www.cysticfibrosismaleinfertility.com/Before_you_begin.html.</a> Look under PROBABILITIES OF INHERITING CF (it's near the top). You and your girlfriend will fall under either B. or C. Your child will for sure be a carrier, because you pass 1 of your 2 DNA strands on Chromosome 7 and BOTH of your strands have a CF mutation on them (hence you having CF) your child will be a carrier. If your GF is a carrier, you will have a 50% of the baby having CF, and a 50% chance of the baby just being a carrier. If your GF is NOT a carrier, the baby will have 100% chance of being JUST a carrier.

I hope that answers your question.

Julie (wife to Mark 24 w/CF)
 

anonymous

New member
Ok, the link isn't working so go to www.cysticfibrosismaleinfertility.com (you may need to cut and paste), then go to Before you begin (third option on the Lefthand side)

Julie (wife to Mark 24 w/CF)
 

seasprite

New member
Yes. If you have cf, you must have <u>two</u> mutated cf genes. Every child you have will inherit one of those genes from you and thus be a carrier, no matter who the mother is. If your girlfriend is not a carrier herself, then any children with her will be carriers only; that is, they will carry a single cftr gene that they can pass on to their own children, but they will not have the disease themselves. If your girlfriend is a carrier, then each of your children with her has a 50% chance of having cf. The problem is that over 1,000 different cf mutations have already been identified and there are probably more to be found. So even if your girlfriend tests negative for all the known mutations, there still is a remote possiblity that she carries one that either hasn't been catalogued yet or that isn't covered by the tests now available. (My husband carries a rare mutation that doesn't show up in routine screening.) So, as usual in life, there are no guarantees. However, some mutations are much more common than others, so the genetic screening you're proposing will at least arm you with the best predicitive information you can get.


Bambi, mom of Jordan, 16 w cf
 
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