<SPAN class=postbody>Hi there, My daughter hasn't been diagnosed with CF so I hope you don't mind me posting here. I am very concerned that she is a sufferer of CF despite having a negative heel prick test. I will tell you a little history on her... She was born a healthy 8lb 10oz and thrived on breastmilk for the first 3 months - staying around the 50th - 75th percentile. By 16 weeks, she had dropped to the 25th and that decline has continued with her now being only about the 4th. She is 15 months old and weighs 17lb 2oz. She caught her first cold when she was 3 weeks old but has an older brother who had just started nursery at the time, so we expected her to pick up various germs. At 9 weeks old, she was hospitalised with bronchiolitis (negative RSV test) following a 2 day stay in hospital with me and her brother after he contracted severe croup, so I put it down to her picking up some nasty germs in the hospital (she was being breastfed so had to stay with us). 10 days after the bronichiolitis, she developed a chest infection and had her first course of antibiotics. At 6 months old, she once again contracted bronichiolitis and we ended up in hospital for 4 days with severe breathing difficulties. She had two bugs growing on her culture, was positive for RSV this time and was put on antibiotics, steroids and hourly nebulizer before switching to salbutamol inhaler. Ever since then, she has had an infection every 4 weeks. She was referred to hospital for her poor weight gain and although the Paediatrician wasn't concerned about her size (her brother started off life on the 50% percentile and steadily dropped to around the 9th), she did request to see her again in 3 months to monitor her chest and consider putting her on a becotide inhaler to try to prevent the frequency of these infections. After a bad infection last month, she was put on becotide a month before her appointment back at the hospital (which is tomorrow). Last week, she developed another horrendous infection requiring antibiotics and steroids as well as her inhaler. She finished her antibiotics yesterday and today, is crackly and wheezy again. We have been to the out of hours doctors and they haven't prescribed anything yet as they want the hospital to hear how she sounds when she is in the midst of an infection. From your experience with CF, am I right to be concerned or is this just asthma? I am going to request a sweat test tomorrow as I cannot get the thought out of my mind. This many infections is not normal in my eyes. Whilst I had childhood asthma, I did not suffer in this way. I know RSV can leave the lungs susceptible for up to 2 year afterwards (according to the Paediatrician at our first appointment) but this every month without fail is just ridiculous and I hate seeing my little girl so unwell all the time. I would be very grateful of any thoughts or advice you might have. Thanks</SPAN>