My son with CF, now almost 4, had bad reflux for about his first 18 months or so. We quite literally had to keep him upright 24 hours a day or his food would roll out of him...we bought a lazy-boy recliner and just took turns holding him while he ate or slept. He took zantac until this past summer then switched to prilosec and it's under control. He still gets hiccups easily and the switch to prilosec was because he was starting to complain of stomach acid bubbling up into his throat after eating. I think the combination of starting more solid foods plus getting bigger/stronger as he grew plus strict compliance with his enzymes and antacids is what got him to the point where he could finally sleep lying down.
I hope you get to the bottom of your little guy's troubles.
I hope you get to the bottom of your little guy's troubles.