Have you told your clinic that the afrin is not going to work? What kind of symptoms does he have? Coughing and sneezing or more like vomitting and diarhea? Does he have a fever? If so, how long has he had a fever. Our doc says if symptoms last for more than three days to bring our DD in. Depending on what he is sick with it could possibly become an infection. It could also be viral, in which case you usually have wait it out. Is he on antibiotics currently for whatever he is culturing? We also increase breathing treatments and CPT when DD shows increased coughing and sneezing. I would definitely call the clinic back, I would also speak with my peditrician, I usually call both, because one is bound to get back to me quickly. I hope this helps. You might also want to post this in the families section to see what others have to say.