Starting Pulmozyme

[amber682]

My son started pulmozyme around 6 months old and I didn't notice any increase in cough. I don't notice any change in him, but consider it more of a preventative thing.

Both of my kids culture staph and we don't treat it unless there's some sort of symptoms, but I don't think its considered normal flora.

My son's yearly x-rays always show "changes consistent with cystic fibrosis".

 

[amber682]

My son started pulmozyme around 6 months old and I didn't notice any increase in cough. I don't notice any change in him, but consider it more of a preventative thing.

Both of my kids culture staph and we don't treat it unless there's some sort of symptoms, but I don't think its considered normal flora.

My son's yearly x-rays always show "changes consistent with cystic fibrosis".

 

[amber682]

My son started pulmozyme around 6 months old and I didn't notice any increase in cough. I don't notice any change in him, but consider it more of a preventative thing.

Both of my kids culture staph and we don't treat it unless there's some sort of symptoms, but I don't think its considered normal flora.

My son's yearly x-rays always show "changes consistent with cystic fibrosis".

 

[amber682]

My son started pulmozyme around 6 months old and I didn't notice any increase in cough. I don't notice any change in him, but consider it more of a preventative thing.

Both of my kids culture staph and we don't treat it unless there's some sort of symptoms, but I don't think its considered normal flora.

My son's yearly x-rays always show "changes consistent with cystic fibrosis".

 

[amber682]

My son started pulmozyme around 6 months old and I didn't notice any increase in cough. I don't notice any change in him, but consider it more of a preventative thing.
<br />
<br />Both of my kids culture staph and we don't treat it unless there's some sort of symptoms, but I don't think its considered normal flora.
<br />
<br />My son's yearly x-rays always show "changes consistent with cystic fibrosis".

 

[Ratatosk]

1. Why isn't she coughing any more than prior to starting treatment?! <b>DS doesn't usually cough unless he does have issues and then we're to call his doctor.</b>

2. Don't all individuals (CF or not) culture staph as "normal" oropharyngeal flora? I understand that CF makes staph infections more complicated, however, her level of staph certainly isn't causing increased respiratory symptoms as they pertain to coughing more often. This was not my understanding. <b>DS has cultured normal flora, not staph. </b>
3. I am not a parent in denial - I understand the cycle of inflammation/infection and fibrosing of lung tissue - however, what are your thoughts regarding radiologist reviews with a given history of CF and "seeing what they want to see" in the radiograph? <b>DS has gotten reports from the local clinic of infiltration, thickening, etc. yet when he goes to a children's hospital for more advanced cts and lung scans, in the past they've shown up as clear. Sometimes I think that the local radiologists just don't have enough experience with people wcf...</b>

4. How immediate upon starting Pulmozyme did you or your little one experience an increase in cough/clearing of mucus? <b>Prior to being on pulmozyme I had never ever seen his nose run. The first thing I noticed was his nose started running. I mean I was totally AMAZED. Sounds weird, I know. And he SOMETIMES (very rarely), will develop a throaty, frog in the throat mucusy sound. Figure he's gots some stuff that needs to be cleared out.</b>

 

[Ratatosk]

1. Why isn't she coughing any more than prior to starting treatment?! <b>DS doesn't usually cough unless he does have issues and then we're to call his doctor.</b>

2. Don't all individuals (CF or not) culture staph as "normal" oropharyngeal flora? I understand that CF makes staph infections more complicated, however, her level of staph certainly isn't causing increased respiratory symptoms as they pertain to coughing more often. This was not my understanding. <b>DS has cultured normal flora, not staph. </b>
3. I am not a parent in denial - I understand the cycle of inflammation/infection and fibrosing of lung tissue - however, what are your thoughts regarding radiologist reviews with a given history of CF and "seeing what they want to see" in the radiograph? <b>DS has gotten reports from the local clinic of infiltration, thickening, etc. yet when he goes to a children's hospital for more advanced cts and lung scans, in the past they've shown up as clear. Sometimes I think that the local radiologists just don't have enough experience with people wcf...</b>

4. How immediate upon starting Pulmozyme did you or your little one experience an increase in cough/clearing of mucus? <b>Prior to being on pulmozyme I had never ever seen his nose run. The first thing I noticed was his nose started running. I mean I was totally AMAZED. Sounds weird, I know. And he SOMETIMES (very rarely), will develop a throaty, frog in the throat mucusy sound. Figure he's gots some stuff that needs to be cleared out.</b>

 

[Ratatosk]

1. Why isn't she coughing any more than prior to starting treatment?! <b>DS doesn't usually cough unless he does have issues and then we're to call his doctor.</b>

2. Don't all individuals (CF or not) culture staph as "normal" oropharyngeal flora? I understand that CF makes staph infections more complicated, however, her level of staph certainly isn't causing increased respiratory symptoms as they pertain to coughing more often. This was not my understanding. <b>DS has cultured normal flora, not staph. </b>
3. I am not a parent in denial - I understand the cycle of inflammation/infection and fibrosing of lung tissue - however, what are your thoughts regarding radiologist reviews with a given history of CF and "seeing what they want to see" in the radiograph? <b>DS has gotten reports from the local clinic of infiltration, thickening, etc. yet when he goes to a children's hospital for more advanced cts and lung scans, in the past they've shown up as clear. Sometimes I think that the local radiologists just don't have enough experience with people wcf...</b>

4. How immediate upon starting Pulmozyme did you or your little one experience an increase in cough/clearing of mucus? <b>Prior to being on pulmozyme I had never ever seen his nose run. The first thing I noticed was his nose started running. I mean I was totally AMAZED. Sounds weird, I know. And he SOMETIMES (very rarely), will develop a throaty, frog in the throat mucusy sound. Figure he's gots some stuff that needs to be cleared out.</b>

 

[Ratatosk]

1. Why isn't she coughing any more than prior to starting treatment?! <b>DS doesn't usually cough unless he does have issues and then we're to call his doctor.</b>

2. Don't all individuals (CF or not) culture staph as "normal" oropharyngeal flora? I understand that CF makes staph infections more complicated, however, her level of staph certainly isn't causing increased respiratory symptoms as they pertain to coughing more often. This was not my understanding. <b>DS has cultured normal flora, not staph. </b>
3. I am not a parent in denial - I understand the cycle of inflammation/infection and fibrosing of lung tissue - however, what are your thoughts regarding radiologist reviews with a given history of CF and "seeing what they want to see" in the radiograph? <b>DS has gotten reports from the local clinic of infiltration, thickening, etc. yet when he goes to a children's hospital for more advanced cts and lung scans, in the past they've shown up as clear. Sometimes I think that the local radiologists just don't have enough experience with people wcf...</b>

4. How immediate upon starting Pulmozyme did you or your little one experience an increase in cough/clearing of mucus? <b>Prior to being on pulmozyme I had never ever seen his nose run. The first thing I noticed was his nose started running. I mean I was totally AMAZED. Sounds weird, I know. And he SOMETIMES (very rarely), will develop a throaty, frog in the throat mucusy sound. Figure he's gots some stuff that needs to be cleared out.</b>

 

[Ratatosk]

<br />1. Why isn't she coughing any more than prior to starting treatment?! <b>DS doesn't usually cough unless he does have issues and then we're to call his doctor.</b>
<br />
<br />2. Don't all individuals (CF or not) culture staph as "normal" oropharyngeal flora? I understand that CF makes staph infections more complicated, however, her level of staph certainly isn't causing increased respiratory symptoms as they pertain to coughing more often. This was not my understanding. <b>DS has cultured normal flora, not staph. </b>
<br />3. I am not a parent in denial - I understand the cycle of inflammation/infection and fibrosing of lung tissue - however, what are your thoughts regarding radiologist reviews with a given history of CF and "seeing what they want to see" in the radiograph? <b>DS has gotten reports from the local clinic of infiltration, thickening, etc. yet when he goes to a children's hospital for more advanced cts and lung scans, in the past they've shown up as clear. Sometimes I think that the local radiologists just don't have enough experience with people wcf...</b>
<br />
<br />4. How immediate upon starting Pulmozyme did you or your little one experience an increase in cough/clearing of mucus? <b>Prior to being on pulmozyme I had never ever seen his nose run. The first thing I noticed was his nose started running. I mean I was totally AMAZED. Sounds weird, I know. And he SOMETIMES (very rarely), will develop a throaty, frog in the throat mucusy sound. Figure he's gots some stuff that needs to be cleared out.</b>
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<br />
<br />

 

[Rebjane]

I have not noticed that Pulmozyme makes my daughter cough. She has been on it since 2 1/2 years old and it is a preventative type med. What DOES very effectively induce coughing is hypertonic saline. She has been taking this since she was 3 or 4 can't remember exactly; but since the addition of 7% hypertonic saline nebs(which we do 2 times a day) with a mask; she gets over colds more easily, sometimes without added antibitotics. I know you weren't asking specifically about this but this has been our experience.

 

[Rebjane]

I have not noticed that Pulmozyme makes my daughter cough. She has been on it since 2 1/2 years old and it is a preventative type med. What DOES very effectively induce coughing is hypertonic saline. She has been taking this since she was 3 or 4 can't remember exactly; but since the addition of 7% hypertonic saline nebs(which we do 2 times a day) with a mask; she gets over colds more easily, sometimes without added antibitotics. I know you weren't asking specifically about this but this has been our experience.

 

[Rebjane]

I have not noticed that Pulmozyme makes my daughter cough. She has been on it since 2 1/2 years old and it is a preventative type med. What DOES very effectively induce coughing is hypertonic saline. She has been taking this since she was 3 or 4 can't remember exactly; but since the addition of 7% hypertonic saline nebs(which we do 2 times a day) with a mask; she gets over colds more easily, sometimes without added antibitotics. I know you weren't asking specifically about this but this has been our experience.

 

[Rebjane]

I have not noticed that Pulmozyme makes my daughter cough. She has been on it since 2 1/2 years old and it is a preventative type med. What DOES very effectively induce coughing is hypertonic saline. She has been taking this since she was 3 or 4 can't remember exactly; but since the addition of 7% hypertonic saline nebs(which we do 2 times a day) with a mask; she gets over colds more easily, sometimes without added antibitotics. I know you weren't asking specifically about this but this has been our experience.

 

[Rebjane]

I have not noticed that Pulmozyme makes my daughter cough. She has been on it since 2 1/2 years old and it is a preventative type med. What DOES very effectively induce coughing is hypertonic saline. She has been taking this since she was 3 or 4 can't remember exactly; but since the addition of 7% hypertonic saline nebs(which we do 2 times a day) with a mask; she gets over colds more easily, sometimes without added antibitotics. I know you weren't asking specifically about this but this has been our experience.

 

[kitomd21]

CF can complicate "normal flora"...but staph can indeed fall into the "normal" category. How a person with CF is affected by it is another factor.

Normal Flora Organisms of the Nose, Nasopharynx, and Oropharynx
A. Most of the surfaces of the upper respiratory tract (including nasal and oral passages, nasopharynx, oropharynx, and trachea) are colonized by normal flora. These organisms are usually regular inhabitants of these surfaces and rarely cause disease. The regular inhabitants of the nose include:

The most common bacteria found in the nose are staphylococci. These organisms are found just inside the nares and include Staphylococcus aureus and S. epidermidis.
In addition to the staphylococci, aerobic corynebacteria ("diphtheroids") can be cultured from the nasal surfaces.
Small numbers of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae can also be found in the nasopharynx. However, most of these strains are not encapsulated or virulent. It should be noted that nonencapsulated, nontypable H. influenzae has been shown to play a significant role in the pathogenesis of otitis media.


B. The normal flora of the oropharynx also contains a large number of regular bacterial inhabitants.
The nose and the oropharynx contains large numbers of S. aureus and S. epidermidis.
The most important group of microorganisms native to this body niche are the alpha-hemolytic streptococci or viridans streptococci. This group includes S. mitis, S. mutans, S. milleri, and S. salivarius. It is believed that these bacteria act as antagonists against invasion by pathogenic streptococci.
Additionally, cultures from this region usually show large numbers of diphtheroids, Moraxella (formerly Branhamella) catarrhalis, and small Gram-negative cocci related to Neisseria species.

C. The normal flora of these areas have two main functions that play a role in maintaining the healthy state of the host.

The organisms compete with pathogenic organisms for potential attachment sites.
These organisms often produce substances (toxins or acids) which are bactericidal.

see: <a target=_blank class=ftalternatingbarlinklarge href="http://www.atsu.edu/faculty/chamberlain/Website/lectures/lecture/introurt.htm">http://www.atsu.edu/faculty/ch...s/lecture/introurt.htm</a>

 

[kitomd21]

CF can complicate "normal flora"...but staph can indeed fall into the "normal" category. How a person with CF is affected by it is another factor.

Normal Flora Organisms of the Nose, Nasopharynx, and Oropharynx
A. Most of the surfaces of the upper respiratory tract (including nasal and oral passages, nasopharynx, oropharynx, and trachea) are colonized by normal flora. These organisms are usually regular inhabitants of these surfaces and rarely cause disease. The regular inhabitants of the nose include:

The most common bacteria found in the nose are staphylococci. These organisms are found just inside the nares and include Staphylococcus aureus and S. epidermidis.
In addition to the staphylococci, aerobic corynebacteria ("diphtheroids") can be cultured from the nasal surfaces.
Small numbers of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae can also be found in the nasopharynx. However, most of these strains are not encapsulated or virulent. It should be noted that nonencapsulated, nontypable H. influenzae has been shown to play a significant role in the pathogenesis of otitis media.


B. The normal flora of the oropharynx also contains a large number of regular bacterial inhabitants.
The nose and the oropharynx contains large numbers of S. aureus and S. epidermidis.
The most important group of microorganisms native to this body niche are the alpha-hemolytic streptococci or viridans streptococci. This group includes S. mitis, S. mutans, S. milleri, and S. salivarius. It is believed that these bacteria act as antagonists against invasion by pathogenic streptococci.
Additionally, cultures from this region usually show large numbers of diphtheroids, Moraxella (formerly Branhamella) catarrhalis, and small Gram-negative cocci related to Neisseria species.

C. The normal flora of these areas have two main functions that play a role in maintaining the healthy state of the host.

The organisms compete with pathogenic organisms for potential attachment sites.
These organisms often produce substances (toxins or acids) which are bactericidal.

see: <a target=_blank class=ftalternatingbarlinklarge href="http://www.atsu.edu/faculty/chamberlain/Website/lectures/lecture/introurt.htm">http://www.atsu.edu/faculty/ch...s/lecture/introurt.htm</a>

 

[kitomd21]

CF can complicate "normal flora"...but staph can indeed fall into the "normal" category. How a person with CF is affected by it is another factor.

Normal Flora Organisms of the Nose, Nasopharynx, and Oropharynx
A. Most of the surfaces of the upper respiratory tract (including nasal and oral passages, nasopharynx, oropharynx, and trachea) are colonized by normal flora. These organisms are usually regular inhabitants of these surfaces and rarely cause disease. The regular inhabitants of the nose include:

The most common bacteria found in the nose are staphylococci. These organisms are found just inside the nares and include Staphylococcus aureus and S. epidermidis.
In addition to the staphylococci, aerobic corynebacteria ("diphtheroids") can be cultured from the nasal surfaces.
Small numbers of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae can also be found in the nasopharynx. However, most of these strains are not encapsulated or virulent. It should be noted that nonencapsulated, nontypable H. influenzae has been shown to play a significant role in the pathogenesis of otitis media.


B. The normal flora of the oropharynx also contains a large number of regular bacterial inhabitants.
The nose and the oropharynx contains large numbers of S. aureus and S. epidermidis.
The most important group of microorganisms native to this body niche are the alpha-hemolytic streptococci or viridans streptococci. This group includes S. mitis, S. mutans, S. milleri, and S. salivarius. It is believed that these bacteria act as antagonists against invasion by pathogenic streptococci.
Additionally, cultures from this region usually show large numbers of diphtheroids, Moraxella (formerly Branhamella) catarrhalis, and small Gram-negative cocci related to Neisseria species.

C. The normal flora of these areas have two main functions that play a role in maintaining the healthy state of the host.

The organisms compete with pathogenic organisms for potential attachment sites.
These organisms often produce substances (toxins or acids) which are bactericidal.

see: <a target=_blank class=ftalternatingbarlinklarge href="http://www.atsu.edu/faculty/chamberlain/Website/lectures/lecture/introurt.htm">http://www.atsu.edu/faculty/ch...s/lecture/introurt.htm</a>

 

[kitomd21]

CF can complicate "normal flora"...but staph can indeed fall into the "normal" category. How a person with CF is affected by it is another factor.

Normal Flora Organisms of the Nose, Nasopharynx, and Oropharynx
A. Most of the surfaces of the upper respiratory tract (including nasal and oral passages, nasopharynx, oropharynx, and trachea) are colonized by normal flora. These organisms are usually regular inhabitants of these surfaces and rarely cause disease. The regular inhabitants of the nose include:

The most common bacteria found in the nose are staphylococci. These organisms are found just inside the nares and include Staphylococcus aureus and S. epidermidis.
In addition to the staphylococci, aerobic corynebacteria ("diphtheroids") can be cultured from the nasal surfaces.
Small numbers of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae can also be found in the nasopharynx. However, most of these strains are not encapsulated or virulent. It should be noted that nonencapsulated, nontypable H. influenzae has been shown to play a significant role in the pathogenesis of otitis media.


B. The normal flora of the oropharynx also contains a large number of regular bacterial inhabitants.
The nose and the oropharynx contains large numbers of S. aureus and S. epidermidis.
The most important group of microorganisms native to this body niche are the alpha-hemolytic streptococci or viridans streptococci. This group includes S. mitis, S. mutans, S. milleri, and S. salivarius. It is believed that these bacteria act as antagonists against invasion by pathogenic streptococci.
Additionally, cultures from this region usually show large numbers of diphtheroids, Moraxella (formerly Branhamella) catarrhalis, and small Gram-negative cocci related to Neisseria species.

C. The normal flora of these areas have two main functions that play a role in maintaining the healthy state of the host.

The organisms compete with pathogenic organisms for potential attachment sites.
These organisms often produce substances (toxins or acids) which are bactericidal.

see: <a target=_blank class=ftalternatingbarlinklarge href="http://www.atsu.edu/faculty/chamberlain/Website/lectures/lecture/introurt.htm">http://www.atsu.edu/faculty/ch...s/lecture/introurt.htm</a>

 

[kitomd21]

CF can complicate "normal flora"...but staph can indeed fall into the "normal" category. How a person with CF is affected by it is another factor.
<br />
<br /> Normal Flora Organisms of the Nose, Nasopharynx, and Oropharynx
<br />A. Most of the surfaces of the upper respiratory tract (including nasal and oral passages, nasopharynx, oropharynx, and trachea) are colonized by normal flora. These organisms are usually regular inhabitants of these surfaces and rarely cause disease. The regular inhabitants of the nose include:
<br />
<br />The most common bacteria found in the nose are staphylococci. These organisms are found just inside the nares and include Staphylococcus aureus and S. epidermidis.
<br />In addition to the staphylococci, aerobic corynebacteria ("diphtheroids") can be cultured from the nasal surfaces.
<br />Small numbers of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae can also be found in the nasopharynx. However, most of these strains are not encapsulated or virulent. It should be noted that nonencapsulated, nontypable H. influenzae has been shown to play a significant role in the pathogenesis of otitis media.
<br />
<br />
<br />B. The normal flora of the oropharynx also contains a large number of regular bacterial inhabitants.
<br /> The nose and the oropharynx contains large numbers of S. aureus and S. epidermidis.
<br /> The most important group of microorganisms native to this body niche are the alpha-hemolytic streptococci or viridans streptococci. This group includes S. mitis, S. mutans, S. milleri, and S. salivarius. It is believed that these bacteria act as antagonists against invasion by pathogenic streptococci.
<br /> Additionally, cultures from this region usually show large numbers of diphtheroids, Moraxella (formerly Branhamella) catarrhalis, and small Gram-negative cocci related to Neisseria species.
<br />
<br />C. The normal flora of these areas have two main functions that play a role in maintaining the healthy state of the host.
<br />
<br />The organisms compete with pathogenic organisms for potential attachment sites.
<br />These organisms often produce substances (toxins or acids) which are bactericidal.
<br />
<br />see: <a target=_blank class=ftalternatingbarlinklarge href="http://www.atsu.edu/faculty/chamberlain/Website/lectures/lecture/introurt.htm">http://www.atsu.edu/faculty/ch...s/lecture/introurt.htm</a>